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The Role of Resistance Exercise Intensity on Muscle Fibre Adaptations

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Abstract

Although many training variables contribute to the performance, cellular and molecular adaptations to resistance exercise, relative intensity (% 1 repetition maximum [%1RM]) appears to be an important factor. This review summarises and analyses data from numerous resistance exercise training studies that have monitored percentage fibre type, fibre type cross-sectional areas, percentage cross-sectional areas, and myosin heavy chain (MHC) isoform expression. In general, relative intensity appears to account for 18–35% of the variance for the hypertrophy response to resistance exercise. On the other hand, fibre type and MHC transitions were not related to the relative intensity used for training. When competitive lifters were compared, those typically utilising the heaviest loads (≥90% 1RM), that is weightlifters and powerlifters, exhibited a preferential hypertrophy of type II fibres when compared with body builders who appear to equally hypertrophy both type I and type II fibres. These data suggest that maximal hypertrophy occurs with loads from 80–95% 1RM.

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References

  1. Fleck SJ, Kraemer WJ. Resistance training: physiological responses and adaptations (part 3). Phys Sportsmed 1988; 16(5): 63–73

    Google Scholar 

  2. Kraemer WJ, Deschenes MR, Fleck SJ. Physiological adaptations to resistance exercise: implications for athletic conditioning. Sports Med 1988; 6: 246–56

    Article  PubMed  CAS  Google Scholar 

  3. Carson JA. The regulation of gene expression in hypertrophying skeletal muscle. In: Holloszy JO, editor. Exercise and sport sciences reviews. Vol. 25. Baltimore (MD): Williams and Wilkins, 1997: 301–20

    Google Scholar 

  4. Thomason DB. Translational control of gene expression in muscle. In: Holloszy JO, editor. Exercise and sport sciences reviews. Vol. 26. Baltimore (MD): Williams and Wilkins, 1998: 165–90

    Google Scholar 

  5. Kraemer WJ. Hormonal mechanisms related to the expression of muscular strength and power. In: Komi PV, editor. Strength and power in sport. London: Blackwell Scientific, 1992: 64–76

    Google Scholar 

  6. Sale DG. Neural adaptation to strength training. In: Komi PV, editor. Strength and power in sport. London: Blackwell Scientific, 1992: 249–65

    Google Scholar 

  7. Staron RS. Human skeletal muscle fiber types: delineation development, and distribution. Can J Appl Physiol 1997; 22(4): 307–27

    Article  PubMed  CAS  Google Scholar 

  8. Lowe DA, Alway SE. Animal models for inducing muscle hypertrophy: are they relevant for clinical applications in humans? J Orthop Sports Phys Ther 2002; 32(2): 36–43

    PubMed  Google Scholar 

  9. Tihanyi J. Development of explosive strength according to muscle fibre types. Mod Athl Coach 1999; 37(1): 12–5

    Google Scholar 

  10. Fleck SJ, Kraemer WJ. Designing resistance exercise programs. 2nd ed. Champaign (IL): Human Kinetics, 1997

    Google Scholar 

  11. Fry AC. Overload and regeneration during resistance exercise. In: Lehmann M, Foster C, Gastmann U, et al., editors. Overload, performance, incompetence, and regeneration in sport. New York: Kluwer Academic/Plenum Publishers, 1999: 149–62

    Chapter  Google Scholar 

  12. Fleck SJ, Kraemer WJ. The ultimate training system: periodization breakthrough! New York: Advanced Research Press, 1996

    Google Scholar 

  13. Stone MH, O’Bryant H. Weight training: a scientific approach. Minneapolis (MN): Bellwether, 1987

    Google Scholar 

  14. Karvonen MJ, Kentala E, Mustala O. The effects of training on heart rate: a longitudinal study. Ann Med Exp Biol Fenn 1957; 35: 307–15

    PubMed  CAS  Google Scholar 

  15. Van Camp SP. Pharmacologic factors in exercise and exercise testing In: Durstine JL, King AC, Painter PL, et al., editors. ACSM’s resource manual for guidelines for exercise testing and prescription. Philadelphia (PA): Lea & Febiger, 1993: 197–215

    Google Scholar 

  16. Noble BJ, Robertson RJ. Perceived exertion. Champaign (IL): Human Kinetics, 1996

    Google Scholar 

  17. Campos GER, Luecke TJ, Wendeln HK, et al. Muscular adaptations in responses to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol 2002; 88: 50–60

    Article  PubMed  Google Scholar 

  18. Kraemer WJ, Koziris LP. Olympic weightlifting and power lifting. In: Lamb DR, Knuttgen HG, Murray R, editors. Perspectives in exercise science and sports medicine. Vol. 7. Physiology and nutrition for competitive sport. Carmel (IN): Cooper: 1994: 1–54

    Google Scholar 

  19. Adams GR. The role of insulin-like growth factor-I in the regulation of skeletal muscle adaptation to increased loading. In: Komi PV, editor. Exercise and sport sciences reviews. Vol. 26. Baltimore (MD): Williams and Wilkins, 1998: 31–60

    Google Scholar 

  20. Fry AC. Resistance exercise overtraining: neuroendocrine responses. Sports Med 1997; 23(2): 106–29

    Article  PubMed  CAS  Google Scholar 

  21. Fry AC, Staron RS, Hagerman FC, et al. Endocrine responses to three different resistance exercise regimens [abstract]. Med Sci Sports Exerc 1999; 31(5): S269

    Google Scholar 

  22. Kraemer WJ, Marchitelli L, McCurry D, et al. Hormonal and growth factor responses to heavy resistance exercise. J Appl Physiol 1990; 69: 1142–50

    Google Scholar 

  23. Staron RS, Karapondo DL, Kraemer WJ, et al. Skeletal muscle adaptations during early phase of heavy-resistance training in men and women. J Appl Physiol 1994; 76(3): 1247–55

    PubMed  CAS  Google Scholar 

  24. Harber MP, Fry AC, Rubin MR, et al. Skeletal muscle and hormonal adaptations to circuit weight training in untrained men. Scand J Med Sci Sports 2004; 14(3): 176–85

    Article  PubMed  Google Scholar 

  25. Green H, Goreham G, Ouyang J, et al. Regulation of fiber size, oxidative potential, and capillarization in human muscle by resistance exercise. Am J Physiol 1998; 276(45): R591–6

    Google Scholar 

  26. Hather BM, Tesch PA, Buchanan P, et al. Influence of eccentric actions on skeletal muscle adaptations to resistance training. Acta Physiol Scand 1991; 143: 177–85

    Article  PubMed  CAS  Google Scholar 

  27. Roman WJ, Fleckenstein J, Stray-Gundersen J, et al. Adaptations in the elbow flexors of elderly males after heavy-resistance training. J Appl Physiol 1993; 74(2): 750–4

    PubMed  CAS  Google Scholar 

  28. Staron RS, Leonardi MJ, Karapondo DL, et al. Strength and skeletal muscle adaptations in heavy-resistance-trained women after detraining and retraining. J Appl Physiol 1991; 70(2): 631–40

    PubMed  CAS  Google Scholar 

  29. Staron RS, Malicky ES, Leonardi MJ, et al. Muscle hypertrophy and fast fiber type conversions in heavy resistance-trained women. Eur J Appl Physiol 1990; 60: 71–9

    Article  CAS  Google Scholar 

  30. Bell GJ, Wenger HA. Physiological adaptations to velocity-controlled resistance training. Sports Med 1992; 13(4): 234–44

    Article  PubMed  CAS  Google Scholar 

  31. Charette SL, McEvoy L, Pyka G, et al. Muscle hypertrophy response to resistance training in older women. J Appl Physiol 1991; 70(5): 1912–6

    PubMed  CAS  Google Scholar 

  32. Hikida RS, Staron RS, Hagerman FC, et al. Effects of high-intensity resistance training on untrained older men: II. Muscle fiber characteristics in nucleo-cytoplasmic relationships. J Gerontol 2000; 55A(7): B347–54

    Google Scholar 

  33. Bottinnelli R, Schiaffino S, Reggiani C. Force-velocity relations and myosin heavy chain isoform composition of skinned fibers from rat skeletal muscle. J Physiol 1991; 437: 655–72

    Google Scholar 

  34. Bottinnelli R, Betto R, Schiaffino S, et al. Unloaded shortening velocity and myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibers. J Physiol 1994; 478: 341–9

    Google Scholar 

  35. Trappe S, Costill D, Thomas R. Effect of swim taper on whole muscle and single muscle fiber contractile properties. Med Sci Sports Exerc 2001; 32(12): 48–56

    Google Scholar 

  36. Costill DL, Coyle EF, Fink WF, et al. Adaptations in skeletal muscle following strength training. J Appl Physiol 1979; 46(1): 96–9

    PubMed  CAS  Google Scholar 

  37. Hakkinen K, Pakarinen A, Kyröläinen H, et al. Neuromuscular adaptations and serum hormones in females during prolonged power training. Int J Sports Med 1990; 11: 91–8

    Article  PubMed  CAS  Google Scholar 

  38. MacDougall JD, Sale DG, Moroz JR, et al. Mitochondrial volume density in human skeletal muscle following heavy resistance training. Med Sci Sports 1979; 11(2): 164–6

    PubMed  CAS  Google Scholar 

  39. Thorstensson A, Hulten B, von Döbeln W, et al. Effect of strength training on enzyme activities and fibre characteristics in human skeletal muscle. Acta Physiol Scand 1976; 96: 392–8

    Article  PubMed  CAS  Google Scholar 

  40. Brown AB, McCartney N, Sale DG. Positive adaptations to weight-lifting training in the elderly. J Appl Physiol 1990; 69(5): 1725–33

    PubMed  CAS  Google Scholar 

  41. Jansson E, Esbjörnsson M, Holm I, et al. Increase in the proportion of fast-twitch muscle fibers by sprint training in males. Acta Physiol Scand 1990; 140: 359–63

    Article  PubMed  CAS  Google Scholar 

  42. Allemeier CA, Fry AC, Johnson P, et al. Effects of sprint cycle training on human skeletal muscle. J Appl Physiol 1994; 77(5): 2385–90

    PubMed  CAS  Google Scholar 

  43. Prince FP, Hikida RS, Hagerman FC. Human muscle fiber types in powerlifters, distance runners and untrained subjects. Pflugers Arch 1976; 363: 19–26

    Article  PubMed  CAS  Google Scholar 

  44. Fry AC, Allemeier CA, Staron RS. Correlation between myosin heavy chain content and percent fiber type area in human skeletal muscle. Eur J Appl Physiol 1994; 68: 246–51

    Article  CAS  Google Scholar 

  45. Narici MV, Hoppeler H, Kayser B, et al. Human quadriceps cross-sectional area, torque and neural activation during 6 months strength training. Acta Physiol Scand 1996; 157: 175–86

    Article  PubMed  CAS  Google Scholar 

  46. Ratzin Jackson CG, Dickinson AL, Ringel SP. Skeletal muscle fiber area alterations in two opposing modes of resistance-exercise training in the same individual. Eur J Appl Physiol 1990; 61: 37–41

    Article  Google Scholar 

  47. MacDougall JD, Tarnopolsky MA, Chesley A, et al. Changes in muscle protein synthesis following heavy resistance exercise in humans: a pilot study. Acta Physiol Scand 1992; 146: 403–4

    Article  PubMed  CAS  Google Scholar 

  48. Kraemer WJ, Patton JF, Gordon SE, et al. Compatibility of high intensity strength and endurance training on hormonal and skeletal muscle adaptations. J Appl Physiol 1995; 78: 976–89

    PubMed  CAS  Google Scholar 

  49. Chiu LZ, Fry AC, Weiss LW, et al. Relative contribution of force and velocity to peak power across a load spectrum: a preliminary study [abstract]. J Strength Cond Res 2001; 15(3): 391

    Google Scholar 

  50. Schilling BK, Fry AC, Chiu LZF, et al. Myosin heavy chain expression and rate of force development in weight trained males and females [abstract]. J Strength Cond Res 2001; 15(3): 398

    Google Scholar 

  51. Adams GR, Hather BM, Baldwin KM, et al. Skeletal muscle myosin heavy chain composition and resistance training. J Appl Physiol 1993; 4(2): 911–5

    Google Scholar 

  52. Faigenbaum A. Age- and sex-related differences and their implications for resistance exercise. In: Baechle TR, Earle RW, editors. Essentials of strength training and conditioning. 2nd ed. Champaign (IL): Human Kinetics, 2000: 169–86

    Google Scholar 

  53. Alway SE, Grumbt WH, Gonyea WJ, et al. Contrasts on muscle and myofibers of elite male and female bodybuilders. J Appl Physiol 1989; 67(1): 24–31

    PubMed  CAS  Google Scholar 

  54. MacDougall JD, Sale DG, Elder GCB, et al. Muscle ultrastructural characteristics of elite powerlifters and bodybuilders. Eur J Appl Physiol 1982; 48: 117–26

    Article  CAS  Google Scholar 

  55. Staron RS. The classification of human skeletal muscle fiber types. J Strength Cond Res 1997; 11(2): 67

    Google Scholar 

  56. Hoeger WWK, Barette SL, Hale DF, et al. Relationship between repetitions and selected percentages of one repetition maximum. J Appl Sport Sci Res 1987; 1(1): 11–3

    Google Scholar 

  57. Lander J. Maximum based on reps. Natl Strength Cond Assoc J 1984; 6(6): 60–1

    Article  Google Scholar 

  58. Zatsiorsky VM. Science and practice of strength training. Champaign (IL): Human Kinetics, 1995

    Google Scholar 

  59. Häkkinen K, Pakarinen A. Acute hormonal responses to two different fatiguing heavy-resistance protocols in male athletes. J Appl Physiol 1993; 74: 882–7

    PubMed  Google Scholar 

  60. Schilling BK, Fry AC, Ferkin MH, et al. Hormonal responses to free-weight and machine exercise [abstract]. Med Sci Sports Exerc 2001; 33 (5 Suppl. 1): S270

    Google Scholar 

  61. Tesch PA. Training for bodybuilding. In: Komi PV, editor. Strength and power in sport. London: Blackwell Scientific, 1992: 370–80

    Google Scholar 

  62. Mikesky AE, Matthews W, Giddings CJ, et al. Muscle enlargement and exercise performance in the cat. J Appl Sport Sci Res 1989; 3(4): 85–92

    Google Scholar 

  63. Garhammer J, Takano B. Training for weightlifting. In: Komi PV, editor. Strength and power in sport. London: Blackwell Scientific, 1992: 357–69

    Google Scholar 

  64. Fry AC, Ryan AJ, Schwab RJ, et al. Anthropometric characteristics as discriminators of body building success. J Sports Sci 1991; 9: 23–32

    Article  PubMed  CAS  Google Scholar 

  65. Bell DG, Jacobs I. Velocity specificity of training in bodybuilders. Can J Sport Sci 1992; 17(1): 28–33

    PubMed  CAS  Google Scholar 

  66. Fry AC, Harber MP, Vaczi M, et al. Muscle fiber characteristics of competitive power lifters. J Strength Cond Res 2003 May; 17(2): 402–10

    PubMed  Google Scholar 

  67. Fry AC, Schilling BK, Staron RS, et al. Muscle fiber characteristics and performance correlates of male Olympic-style weightlifters. J Strength Cond Res 2003; 17(4): 746–54

    PubMed  Google Scholar 

  68. Tesch PA, Larsson L. Muscle hypertrophy in body builders. Eur J Appl Physiol 1982; 49: 301–6

    Article  CAS  Google Scholar 

  69. Tesch PA, Thorsson A, Kaiser P. Muscle capillary supply and fiber type characteristics in weight and power lifters. J Appl Physiol 1984; 56: 35–8

    PubMed  CAS  Google Scholar 

  70. Rubin MR, Harber MP, Fry AC, et al. Endocrine responses to 10 weeks of circuit weight training [abstract]. J Strength Cond Res 1999; 13(4): 432

    Google Scholar 

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Acknowledgements

The preparation of this paper was supported, in part, by funding from the National Strength and Conditioning Association, USA-Weightlifting and the University of Memphis Research Grant programme. The author has no conflicts of interest that are directly relevant to the content of this review.

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    Andrew C. Fry

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Fry, A.C. The Role of Resistance Exercise Intensity on Muscle Fibre Adaptations. Sports Med 34, 663–679 (2004). https://doi.org/10.2165/00007256-200434100-00004

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