Chest
Clinical InvestigationsSLEEP AND BREATHINGPrevalence of Sleep Apnea Syndrome in Lone Atrial Fibrillation: A Case-Control Study
Section snippets
Study Population
We identified AF cases among patients treated for lone AF in Jyva¨skyla¨ Central Hospital (JCH). The hospital database included 699 patients with International Classification of Diseases, Tenth Revision diagnosis I48 (AF/atrial flutter) in 1999. Assessing hospital patient files, we classified AF as lone if the patient did not have any of the known causes of AF: hypertension, ischemic heart disease, valvular heart disease, and hyperthyroidism; and acute causes: alcohol intake, surgery,
Characteristics of the Study Population
Mean time between the last visit to JCH and sleep recording in the AF group was 24 months (SD, 4 months). At the time of sleep recording in the AF group, 39 patients (66%) received a beta-blocker, 20 patients (34%) received flecainide, 4 patients (7%) received amiodarone, 4 patients (7%) received digoxin, 1 patient (2%) received quinidine sulfate, and 18 patients (31%) received warfarin. All control subjects were in sinus rhythm, had normal S-TSH, and were clinically euthyroid.
Table 1 shows the
Discussion
To the best of our knowledge, this may be the first report of the prevalence of SAS in lone AF. Using same cut-off values for SAS as in a recent study,20 AI ≥ 5 plus AHI ≥ 15, the prevalence of SAS in lone AF was 32%, which is higher than that in population-based trials.3 In a population-based study, Sjöström et al21 reported sleep-disordered breathing in 31% of hypertensive men. We did not exclude subjects by BP measurements made just before they joined the study. It would, in fact, have been
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Polysomnography in AF patients without prior diagnosis of obstructive sleep apnea reveals significant sleep abnormality: A strong case for screening in all patients with atrial fibrillation?
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2018, Cardiac Electrophysiology: From Cell to Bedside: Seventh EditionRehabilitation of Cardiovascular Disorders and Sleep Apnea
2017, Sleep Medicine ClinicsCitation Excerpt :There is growing evidence that treatment of coexisting OSA with continuous positive airway pressure (CPAP) or mandibular advancement devices can successfully treat OSA, resulting in improved rehabilitation outcomes and improved health-related quality of life.12–15 It is well known that patients with different types of cardiovascular diseases have higher prevalence of SDB.16–19 Several studies have shown that OSA is an independent risk factor for development of hypertension and has a dose-response relationship between severity of OSA and incidence of hypertension.18,20,21
This work was performed at Jyva¨skyla¨ Central Hospital, Jyva¨skyla¨, Finland.
This study was supported by The Finnish Anti-Tuberculosis Association Foundation, The Ida Montin Foundation, The Va¨inö and Laina Kivi Foundation, The Pa¨ivikki and Sakari Sohlberg Foundation, and an EVO (erityisvaltionosuusraha) grant from Jyva¨skyla¨ Central Hospital.