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ESCMID guidelines for the management of the infection control measures to reduce transmission of multidrug-resistant Gram-negative bacteria in hospitalized patients

https://doi.org/10.1111/1469-0691.12427Get rights and content
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Abstract

Healthcare-associated infections due to multidrug-resistant Gram-negative bacteria (MDR-GNB) are a leading cause of morbidity and mortality worldwide. These evidence-based guidelines have been produced after a systematic review of published studies on infection prevention and control interventions aimed at reducing the transmission of MDR-GNB. The recommendations are stratified by type of infection prevention and control intervention and species of MDR-GNB and are presented in the form of ‘basic’ practices, recommended for all acute care facilities, and ‘additional special approaches’ to be considered when there is still clinical and/or epidemiological and/or molecular evidence of ongoing transmission, despite the application of the basic measures. The level of evidence for and strength of each recommendation, were defined according to the GRADE approach.

Keywords

Acinetobacter
Burkholderia
Enterobacteriaceae
extended-spectrum β-lactamase
guideline
infection control
multidrug-resistant Gram-negative
outbreak
Pseudomonas
Stenotrophomonas

Cited by (0)

These guidelines are endorsed by Società Italiana Malattie Infettive e Tropicali (SIMIT), Brazilian Association of Professionals in Infection Control and Hospital Epidemiology (ABIH), Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Società Italiana Multidisciplinare per la Prevenzione delle Infezioni nelle Organizzazioni Sanitarie Italiana Malattie (SIMPIOS), Indian Association of Medical Microbiologists Delhi & NCR Chapter (IAMM DC and NCR), and Colombian Association of Hospital Epidemiology (ACEH).