Multimorbidity in older adults with intellectual disabilities
Introduction
It has long been a common understanding, that people with intellectual disabilities (ID) ‘are old from the age of 50 years onwards’ (Perkins and Moran, 2010, Roth et al., 1996). Nevertheless, apart from people with Down syndrome (Roth et al., 1996), premature aging has never been scientifically confirmed for this group. Geriatric frailty occurs early in the population with ID (Evenhuis, Hermans, Hilgenkamp, Bastiaanse, & Echteld, 2012) and is considered to be a risk factor for subsequent deterioration of health and independence (Fried et al., 2001), occurs early in the population with ID. Their mean frailty index scores at age 50–59 years are comparable to those in the general population aged 70–79 years (Schoufour, Mitnitski, Rockwood, Evenhuis, & Echteld, 2013). This early occurrence of frailty might be an explanation for the perceived early aging.
Frailty might be partly caused by multimorbidity, which refers to the occurrence of two or more chronic conditions. The prevalence of multimorbidity has been extensively studied in older people with normal intelligence (Glynn et al., 2011, Schram et al., 2008, Van Oostrom et al., 2011). The results of these studies imply that prevalence increases with age and is related to female gender, lower education and low social-economic status (Marengoni et al., 2008, Salisbury et al., 2011, Tucker-Seeley et al., 2011, Uijen and van de Lisdonk, 2008). Despite the numerous studies, treatment options are still vague. Physicians seem to treat each disease separately and show little attention for the synergy between different diseases (Bower et al., 2012), whereas lack of good treatment causes ongoing functional decline, impaired quality of life and early death (Drewes et al., 2011, Fortin et al., 2006, Hunger et al., 2011, Landi et al., 2010).
People with ID seem to have an increased risk of chronic multimorbidity (McCarron et al., 2013) for several reasons. Multimorbidity may start at a young age, with conditions related to brain damage, impaired brain development, and etiologic syndromes. For example, people with cerebral palsy often have motor impairment, epilepsy and other neurologic problems (Arvio & Sillanpaa, 2003). What is more, risks to develop age-related conditions may be different because of superpositioning on childhood conditions and other unfavorable factors (De Winter, Bastiaanse, Hilgenkamp, Evenhuis, & Echteld, 2012). For instance, an increased risk of cardiovascular risk factors is found both in young and older adults with ID (De Winter et al., 2012, Emerson, 2005, Haveman et al., 2011). This may not only be attributable to an unhealthy lifestyle, but also to metabolic effects of antipsychotic drug use (De Kuijper et al., 2013) and fragmented sleep–wake rhythms (Maaskant, van de Wouw, van Wijck, Evenhuis, & Echteld, 2013).
Nevertheless, medical care for this group is primarily reactive, i.e. if complaints or observed symptoms are brought to the attention of the physician (Lennox, Diggens, & Ugoni, 1997). Multimorbidity and frail unhealthy life-years may be delayed by treating conditions that are to be expected during early and later adulthood, as well as anticipating healthcare, aimed at prevention and pro-active diagnosis. Consequently, healthcare costs will decrease because of less dependency caused by additional diseases.
To improve healthcare for people with ID, more knowledge on multimorbidity is necessary (McCarron et al., 2013). Therefore, we studied the prevalence and associated factors of chronic multimorbidity in the broad client population, aged 50 years and over, of Dutch intellectual disability service providers. We have also studied the presence of meaningful clusters of multimorbidity, as a basis for anticipating healthcare.
Section snippets
Design and study population
This study was part of the cross-sectional ‘Healthy Ageing and Intellectual Disabilities’ (HA-ID) study. This study has been performed in a consort of three large formal ID service providers in the south and west of the Netherlands in both rural and urban environments. These service providers provide care (e.g. washing, nursing) and support (e.g. helping with finances, housekeeping) to a broad spectrum of clients. They cover different levels of support needs: centralized residential
Results
Data on two or more of the chronic conditions were available for 1047 participants with a mean age of 60.9 years (s.d. = 8.1). The characteristics of the study population are described in Table 2. Non-participants (n = 1275) and participants (n = 1047) were not significantly different for age (t = 1.16, df = 2320, p = 0.25), but men (χ2 = 5.10, df = 1, p = 0.02) and people living independently (χ2 = 90.11, df = 4, p = 0.00) were underrepresented in the sample. In the total study sample, the mean number of chronic
Discussion
The results of this study show that multimorbidity (≥2 conditions) is a large problem in older adults (≥50 years) with ID, affecting 80% of the population. Moreover, 47% of the older adults with ID had four or more chronic conditions. As was to be expected, multimorbidity rates increase with age. In addition to this, people with severe or profound ID suffer more often from multimorbidity (both ≥2 and ≥4 conditions) and people with Down syndrome had more often four or more conditions.
Acknowledgements
We thank the participants and professionals of the participating ID service providers, Abrona, Amarant, and Ipse de Bruggen, for their enthusiastic cooperation in this study.
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