Asthma diagnosis and treatmentInternet-based monitoring of asthma: A long-term, randomized clinical study of 300 asthmatic subjects
Section snippets
Study design
The study was carried out in a 6-month, prospective, randomized comparative design with 3 parallel groups and 2 scheduled visits 6 months apart. At each visit, questionnaires were filled in, spirometry was performed, measurement of airway responsiveness with methacholine was conducted, and each patient was interviewed by the physician. The patients were randomized consecutively by using the sealed envelope technique, irrespective of computer experience and smoking status, to one of the
Results
We enrolled 300 subjects who fulfilled the criteria for asthma. There were no significant differences among the 3 groups at baseline (Table I). Two hundred fifty-three subjects completed both the screening and follow-up visits. No significant difference was found in the dropout rate of the 3 groups (15, 12, and 20 subjects, respectively; P = .26, χ2).
Discussion
A Cochrane review27 demonstrates that asthma is better controlled if patients, self-monitoring their symptoms and peak flow, follow a written action plan and attend regular control visits to their physician's office. But it can be quite complicated to handle for both patients and physicians, and therefore Internet-based management systems have been developed to try to improve user-friendliness in self-management and monitoring.
This randomized controlled study is one of a very few similar
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Supported by grants from H:S Corporation of University Hospital of Copenhagen, AstraZeneca, and private funds, none of whom had any role in writing the protocol; collecting, analyzing, or interpreting the data; or writing of the article.
Disclosure of potential conflict of interest: A grant, managed by V. Backer, was given by AstraZeneca. K. Phanareth was employed as a consultant on an hourly basis by AstraZeneca DK during the first 2 years of the project, No other conflicts of interest are disclosed.