Elsevier

Fertility and Sterility

Volume 82, Issue 2, August 2004, Pages 374-377
Fertility and Sterility

Male factor
Effects of alcohol and cigarette consumption on human seminal quality

https://doi.org/10.1016/j.fertnstert.2004.03.022Get rights and content
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Abstract

Objective

To evaluate the effects of alcohol or cigarette consumption on seminal parameters in a large population of men attending an andrology laboratory.

Design

Analysis of ten years of data (1990–1999).

Setting

Andrology and Reproduction Laboratory (Córdoba, Argentina).

Patient(s)

Patients (3,976) were grouped according to nonsmokers; ≤20 cigarettes/day; >20 cigarettes/day; nonalcohol consumers; ≤500 mL of wine (∼52 g of ethanol) or equivalent/day; and >500 mL of wine or equivalent/day. Patients who drank alcohol and smoked were also considered.

Intervention(s)

A questionnaire was voluntarily filled out by patients. It provided data on drug consumption and genitourinary diseases.

Main outcome measure(s)

Seminal volume, sperm concentration, motility, viability, and morphology.

Results

No statistical differences in seminal parameters were found between the degrees of alcohol or tobacco consumption; so, independently of the degree of consumption patients were considered as smokers or alcohol consumers.

Conclusion(s)

Alcohol or cigarette consumption did not alter the seminal parameters. Nevertheless, when the patients with these two habits were compared to those without these habits, a significant reduction in seminal volume, sperm concentration, percentage of motile spermatozoa, and a significant increase of the nonmotile viable gametes were detected. The synergic or additive effect of these two toxic habits is discussed.

Keywords

Alcohol
tobacco
cigarette smoking
human semen
sperm functional activity
sperm morphology
human reproduction

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Supported by grants from the Agencia Córdoba Ciencia (ACC S.E.), FONCyT and Secretaría de Ciencia y Tecnología (SECyT), UNC.