Coronary artery diseaseComparison of Treatment and Outcome of Acute Coronary Syndrome in Patients With Versus Patients Without Diabetes Mellitus
Section snippets
Methods
The details of the EHS-ACS-II have been previously described.1 The survey was conducted in 190 volunteering medical centers from 32 member countries of the EHS. Enrolment began March 2004 and ended October 2004. Participating centers were asked to recruit 30 to 50 consecutive patients fulfilling the survey inclusion criterion of a confirmed diagnosis of ACS. In addition to data regarding the prehospital and in-hospital course, follow-up data were collected using telephone interview or personal
Results
Of 6,385 patients with a final diagnosis of ACS enrolled in the EHS-ACS-II, documentation of DM status was available for 6,349 (99%). DM was reported in 1,587 patients (25.0%), 24.9% of whom were treated using insulin and 54.0% were treated using oral hypoglycemic medication. Baseline characteristics of patients with ACS with and without DM presenting with STE and non-STE ACS are listed in Table 1. Patients with DM were significantly older, were more often women, and had higher prevalences of
Discussion
In our analysis, 25% of patients with ACSs had known DM on admission. This was similar to results from previous large-scale clinical surveys2, 3 and the previous Euro Heart Survey ACS-I, in which 23% had a previous diagnosis of DM.4 It was previously recognized that patients with ACS with DM comprised a distinctive risk group in patients with ACSs. We found that patients with DM in our cohort had a less favorable risk-factor profile and more previous diagnoses of cardiovascular and renal
Acknowledgment
Dr. Hasin had full access to all data in the study and takes responsibility for the integrity of the data and accuracy of data analysis.
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