Original contributionA prospective, population-based study of acute ibuprofen overdose: Complications are rare and routine serum levels not warranted
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Cited by (45)
Massive ibuprofen ingestion in an adolescent treated with plasma exchange
2020, Toxicology Cases for the Clinical and Forensic LaboratoryIbuprofen
2014, Encyclopedia of Toxicology: Third EditionNonsteroidal anti-inflammatory drugs exposure and the central nervous system
2014, Handbook of Clinical NeurologyCitation Excerpt :Acute CNS toxicity related to NSAID use is pervasive and varied. A prospective study looking at ibuprofen overdose noted that 30% of patients experience CNS effects ranging from drowsiness to coma (McElwee et al., 1990). Case reports have identified numerous neurologic sequelae including ataxia, vertigo, dizziness, recurrent falls, nystagmus, headache, encephalopathy, and disorientation (Neufeld and Korczyn, 1986; Biscarini, 2000).
Ibuprofen-induced hypersensitivity syndrome
2010, Translational ResearchCitation Excerpt :This might have led to an HSR in the case of the 48-year-old woman taking these 2 drugs.97 Clinically consistent interaction between a preexisting conditions and ibuprofen have been reported.33,46,48,49,101-103,110,120-125 A potentially clinically relevant interaction between ibuprofen and aspirin, referred to as “aspirin resistance,” has been observed when ibuprofen is administered before aspirin in patients with rheumatoid arthritis.
Nonsteroidal Anti-Inflammatory Drugs
2007, Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose, Fourth EditionMassive ibuprofen overdose requiring extracorporeal membrane oxygenation for cardiovascular support
2007, Pediatric Critical Care Medicine
Presented in part at the AAPCC/AACT/ ABMT/CAPCC Annual Meeting in Santa Fe, New Mexico, September 1986.
Supported by a grant from Whitehall Laboratories, New York, New York.