Elsevier

The Lancet

Volume 354, Issue 9186, 9 October 1999, Pages 1227-1228
The Lancet

Commentary
Diagnosing dementia with Lewy bodies

https://doi.org/10.1016/S0140-6736(99)90214-3Get rights and content

References (15)

  • C Holmes et al.

    Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies

    Br J Psychiatry

    (1999)
  • L Hansen et al.

    The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity

    Neurology

    (1990)
  • IG McKeith et al.

    Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

    Neurology

    (1996)
  • I McKeith et al.

    Neuroleptic sensitivity in patients with senile dementia of Lewy body type

    BMJ

    (1992)
  • Curr Probl Pharmacol

    (1994)
  • C Shea et al.

    Donepezil for treatment of dementia with Lewy bodies: a case series of nine patients

    Int Psychogeriatr

    (1998)
  • GG Lennox et al.

    The clinical diagnosis and misdiagnosis of Lewy body dementia

There are more references available in the full text version of this article.

Cited by (55)

  • An improved I-FAST system for the diagnosis of Alzheimer's disease from unprocessed electroencephalograms by using robust invariant features

    2015, Artificial Intelligence in Medicine
    Citation Excerpt :

    Neuroimaging diagnostic procedures (MRI) and complete laboratory analyses were carried out to exclude other causes of progressive or reversible dementias, in order to have a clinically homogenous mild AD group. Exclusion criteria were any evidence of: (i) fronto-temporal dementia [28]; (ii) vascular dementia, diagnosed according to NINDS-AIREN criteria [29]; (iii) extra-pyramidal syndromes; (iv) reversible dementias (including pseudodementia of depression); and (v) Lewy body dementia, according to the criteria in McKeith [30]. Finally, the CTR subjects were recruited mostly from non-consanguineous relatives of AD patients.

  • The diagnostic utility of cerebrospinal fluid alpha-synuclein analysis in dementia with Lewy bodies - A systematic review and meta-analysis

    2013, Parkinsonism and Related Disorders
    Citation Excerpt :

    Citation tracing, bibliographic review of references in relevant studies and hand searching were also performed in order to ensure all relevant studies were included. Studies were included if they, 1) Involved reproducible methods of quantification of CSF alpha-synuclein, 2) Included a representative spectrum of patients encountered in clinical practice and 3) Classified patient groups using internationally agreed consensus criteria such as the McKeith criteria for DLB [6–9], the National Institute of Neurological, Communicative Diseases and Stroke – Alzheimers Disease and Related Disorders Association (NINCDS-ADRDA) criteria for AD [10], United Kingdom Parkinsons Disease Society (UKPDS) Brain Bank criteria for PD [11] and Lund-Manchester criteria for fronto-temporal dementia [12]. Studies were excluded if they measured CSF alpha-synuclein from post-mortem samples, measured plasma alpha-synuclein, included patients with mixed pathologies or uncertain diagnosis, or made no attempt of excluding other structural causes of cognitive decline.

  • Impairments of speech fluency in Lewy body spectrum disorder

    2012, Brain and Language
    Citation Excerpt :

    We predicted that there would be widespread cortical atrophy in LBSD and that reduced fluency in these patients would be related to prefrontal disease. We studied 35 non-aphasic patients with LBSD, diagnosed in the Cognitive Neurology or Movement Disorders clinics of the Department of Neurology at the University of Pennsylvania by experienced neurologists (RGG, AS, MG) according to published criteria (Hughes, Daniel, Kilford, & Lees, 1992; McKeith, O’Brien, & Ballard, 1999; McKeith et al., 1996, 2005). The non-demented group consisted of 21 patients with PD.

  • The organization of narrative discourse in lewy body spectrum disorder

    2011, Brain and Language
    Citation Excerpt :

    We also hypothesized that limited organizational attributes of LBSD narratives would be related to cortical atrophy affecting prefrontal cortex. We studied 32 non-aphasic patients with LBSD, diagnosed in the Cognitive Neurology or Movement Disorders clinics of the Department of Neurology at the University of Pennsylvania by experienced neurologists (RGG, AS, MG) according to published criteria (Hughes, Daniel, Kilford, & Lees, 1992; McKeith, O’Brien, & Ballard, 1999; McKeith et al., 1996, 2005). Fourteen patients exhibited evidence of dementia (DLB/PDD), and 18 were not demented (PD).

  • Dorsal Motor Nucleus of Vagus protein aggregates in Lewy Body Disease with autonomic dysfunction

    2009, Brain Research
    Citation Excerpt :

    Diagnoses were made by operationalised criteria for PD and DLB which have been validated against neuropathological diagnosis within our group. PDD patients met both UKPDS Brain bank criteria and DLB consensus criteria, with the exception that the motor disorder preceded dementia by more than 12 months (McKeith et al., 1999). Participants received a full medical assessment, including physical examination and 12 lead electrocardiogram.

View all citing articles on Scopus
View full text