Original researchMaternal hemoglobin and risk of gestational diabetes mellitus in Chinese women
Section snippets
Materials and methods
Our hospital is a government-funded regional hospital with about 5000 deliveries per annum, and caters mainly to residents of Hong Kong who do not have to pay for antenatal care. The majority of our patients (more than 95%) is ethnic Chinese. A multivitamin preparation containing 29 mg of elemental iron is offered to all patients from 20 weeks’ gestation, but patients’ compliance is not monitored. At the first antenatal visit, maternal hemoglobin concentration, mean corpuscular volume, and
Results
The records of 865 women attending the clinic consecutively were screened, and 780 women who fulfilled the inclusion criteria were approached for recruitment, of whom 762 consented to be studied. However, the results of the serum ferritin and iron concentrations were not available in 32 women, leaving only 730 women in the final analysis. The 75th, 50th, and 25th percentile values of the initial visit hemoglobin concentration were 13.0 g/dL, 12.4 g/dL, and 11.5 g/dL, respectively, and the
Discussion
The measurement of hemoglobin at the first antenatal visit has become a standard investigation in the pregnant woman. This result could be useful for the identification of women who are at risk not only for complications, such as fetal growth restriction and preterm birth, but also for GDM if the association between high hemoglobin concentration and diabetes mellitus found in the nonpregnant woman can also be demonstrated during pregnancy.
In nonpregnant subjects, the association between high
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A study to investigate the elevated maternal haemoglobin value as a risk biomarker for gestational diabetes: A nested case control study
2021, Clinical Epidemiology and Global HealthCitation Excerpt :The inferential statistics using Pearson's correlation test yielded a moderate correlation between the maternal haemoglobin and the development of GDM. The findings of our study were similar to the other studies like Rayis DA et al., Tarim E et al., and Lao TT et al. where they have reported high serum haemoglobin during the pregnancy is an independent risk factor for the development of gestational diabetes mellitus.4,11,12 By analyzing the demographics of the subjects recruited to GDM and non-DM groups of this study, the variables like education, occupation, consanguinity degree, gravida and marital status were equally distributed in both the groups at a p-value >0.05.
Prevalence of ‘Hyperglycemia in pregnancy’ remained stable between 2006 and 2015, despite rise in conventional risk factors: A hospital based study in Delhi, North India
2021, Diabetes Research and Clinical PracticeCitation Excerpt :The conventional GDM risk factors; maternal age, family history of diabetes, history of GDM, multigravidity ≥3 were significantly higher in 2011–2015 period than in earlier period (Table 2). Many unconventional GDM risk factors proposed by other researchers like high haemoglobin level [37] and higher income (in developing countries) [38], increased during that period, while the HBsAg positivity [39], thalassemia [2] and male foetal sex [40] were not identified as GDM risk factors in our study (Table 1). There are pitfalls in assessing the ‘history of GDM’ in the present study.
Prepregnancy hemoglobin levels and gestational diabetes mellitus in pregnancy
2021, Diabetes Research and Clinical PracticeCitation Excerpt :One meta-analysis demonstrated the association between elevated Hb concentrations and GDM [17]. A study on Chinese women also demonstrated that maternal Hb > 13 g/dL at the first antenatal visit was an independent GDM risk factor [16]. Our results support the findings of these studies but none of the previous studies have evaluated prepregnancy Hb levels and the risk of GDM during pregnancy.
Early pregnancy hemoglobin is associated with the risk of gestational diabetes mellitus: a retrospective cohort study
2022, British Journal of Nutrition
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Present address for Louis Y. Chan, MBBS: Department of Obstetrics and Gynecology, Princess Margaret Hospital, Kowloon, Hong Kong, China.