ReviewThe epidemiology of endometrial cancer
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γ-Glutamyl cyclotransferase contributes to endometrial carcinoma malignant progression and upregulation of PD-L1 expression during activation of epithelial-mesenchymal transition
2020, International ImmunopharmacologyCitation Excerpt :Endometrial carcinoma is one of the three major malignant female reproductive system tumors, accounting for 7% of the total number of female malignant tumors [1]. The global incidence of endometrial carcinoma has risen in the last 30 years, particularly in developing countries [2,3]. γ-glutamyl cyclotransferase (GGCT) is a major enzyme in the γ-glutamyl cycle, which mediates synthesis and degradation of glutathione, and may be associated with the transport of amino acids across cellular membranes [4,5].
Preoperative predictors of endometrial cancer at time of hysterectomy for endometrial intraepithelial neoplasia or complex atypical hyperplasia
2020, American Journal of Obstetrics and GynecologyBenign and Premalignant Lesions of the Endometrium
2019, Surgical Pathology ClinicsInduction of uterine hyperplasia after cafeteria diet exposure
2018, Molecular and Cellular EndocrinologyCitation Excerpt :Many risk factors of endometrial cancer have been described such as, early age at menarche, nulliparity, late-onset menopause, exposure to exogenous oestrogens (without a progesterone component), diabetes and obesity (Parazzini et al., 1991; Amant et al., 2005).