Abstract
Complicated urinary tract infection is a challenging infection, since cure is difficult and either persistence or recurrence is common. The challenge is frequently increased because complicated urinary tract infection is often caused by gram-negative bacilli resistant to multiple antimicrobial drugs. In this review, we approach the therapy of complicated urinary tract infection with an emphasis on those caused by antimicrobial drug-resistant gram-negative uropathogens.
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Levison, M.E., Kaye, D. Treatment of Complicated Urinary Tract Infections With an Emphasis on Drug-Resistant Gram-Negative Uropathogens. Curr Infect Dis Rep 15, 109–115 (2013). https://doi.org/10.1007/s11908-013-0315-7
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DOI: https://doi.org/10.1007/s11908-013-0315-7
Keywords
- Complicated
- Urinary tract
- Infection
- Drug resistance
- Gram-negative bacilli
- Uropathogens
- Trimethoprim/sulfamethoxazole
- Fluoroquinolones
- Nitrofurantoin
- Fosfomycin
- Amoxicillin/clavulanic acid
- Third-generation cephalosporins
- Aztreonam
- Beta-lactam/beta-lactamase inhibitor combinations
- Cefepime
- Carbapenems
- ESBL
- AmpC beta-lactamase
- Carbapenemase
- Treatment guidelines