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Bariatric Surgery and Renal Function

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Abstract

Obesity causes a significant healthcare burden and has been shown to be an important risk factor in the development of cardiovascular disease, type 2 diabetes, and increasingly chronic kidney disease. Bariatric surgery is the most effective treatment for obesity and has been shown to drastically improve both blood pressure and diabetic control. However, the interaction of bariatric surgery and renal function is less clear. This review focuses on the effect of bariatric surgery on renal function both in the acute situation, with respect to acute kidney injury, and also on changes in renal function parameters post-bariatric surgery weight loss. The interaction of obesity, bariatric surgery, and nephrolithiasis as a precipitant of acute kidney injury will also be considered. The role of bariatric surgery in pre- and post-renal transplant recipients is discussed as well as possible mechanisms underlying the improvement in renal function.

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Acknowledgements

The authors would like to thank Dr Candice Roufosse (Consultant Histopathologist, Hammersmith Hospital, London, UK) for her expert help in providing the micrograph of obesity-related glomerulopathy seen in the article.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Surgery, Division of Surgery and Cancer, Imperial College London, London, UK

    Andrew Currie & Andrew Chetwood

  2. Dept of Bariatric Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK

    Ahmed R. Ahmed

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  1. Andrew Currie
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  3. Ahmed R. Ahmed
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Correspondence to Ahmed R. Ahmed.

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Currie, A., Chetwood, A. & Ahmed, A.R. Bariatric Surgery and Renal Function. OBES SURG 21, 528–539 (2011). https://doi.org/10.1007/s11695-011-0356-7

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