Abstract
Objectives: Work in greenhouses is performed in warm microclimate during the most time of the year, involves usually moderately intense or heavy work. The working conditions in greenhouses might involve also indirect exposure to pesticides resulting from contact with pesticide-treated flowers and vegetables. The aim of the study was to investigate whether the work in greenhouse during pregnancy adversely influenced infant birth weight and, if so, which of the two main potential hazards typical for such environment (heavy physical work or exposure to pesticides) played the major role in this process. Methods: The list of 14 major greenhouses (each above 5 ha) growing vegetables (cucumbers and tomatoes) was obtained from the Polish Chamber of Horticulture. Between January 2001 and December 2003, 460 women at the age below 45 years, married or who lived with a partner and who had been working for a period of at least 2 years in greenhouses in Poland were asked to participate in the project. We classified pregnancies of women working in, and out of, greenhouses on the basis of energy expenditure during mother’s work into three groups: A (200–700 kcal/shift); B (701–1000 kcal/shift); and C (1001–1200 kcal/shift). Information about application of pesticides in 1997–2001 was received from persons responsible for chemical protection in each examined greenhouse. Trade names of pesticides, names and amounts of the active ingredients, type of cultivation and its area were abstracted from pesticide application registers run by each greenhouse operator. Pesticides were classified as reproductive and developmental (RD) toxins according to Pan American Pesticide Database classification. Results: The mean birth weight of infants whose mothers worked in greenhouse during pregnancy (work expenditure >1000 kcal/shift) was 177 g lower than that of those whose mothers worked out of greenhouse (light work <700 kcal/shift) (p = 0.05). Mothers who during work in greenhouse were potentially exposed to RD pesticides, delivered infants with birth weight lower by about 70 g. than infants’ mothers not working at places where pesticides RD were applied, but these findings were not statistically significant. Conclusion: Our results indicate that infants of mothers performing heavy work inside greenhouse during pregnancy had lower mean birth weight than infants of mothers working out of greenhouse. No similar effects of current exposure to pesticides was observed.
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References
Abell A, Ernst E, Bonde JPE (2000) Semen quality and sexual hormones in greenhouse workers. Scand J Work Environ Health 26(6):492–500
Abell A, Juul S, Bonde JPE (2000) Time to pregnancy among female greenhouse workers. Scand J Work Environ Health 26 (2):131–136
Blair A, Zahm SH (1992) Patterns of pesticide use among farmers: implications for epidemiological research. Epidemiology 4:55–62
Cooper S, Burau K, Sweeney A, Robison T, Smith MA, Symanski E, et al (2001) Prenatal exposure to pesticides:a feasibility study among migrant and seasonal farmworkers. Am J Ind Med 40:578–585
Datta SR, Ramanathan NL (1969) Energy expenditure in work predicted from heart rate and pulmonary ventilation. J Appl Physiol 26:297–302
Dąbrowski S, Hanke W, Polańska K, Makowiec-Dąbrowska T, Sobala W (2003) Pesticide exposure and birthweight:an epidemiological study in Central Poland. Int J Occup Med Environ Health 16(1):31–39
de Cock J, Westveer K, Heederik D, te Velde E, van Kooij R (1994) Time to pregnancy and occupational exposure to pesticides in fruit growers in The Netherlands. Occup Environ Med 51:693–699
Engel LS, O’Meara ES, Schwartz SM (2000) Maternal occupation in agriculture and risk of adverse birth outcomes in Washington State 1980–1991. Am J Epidemiol 26(3):193–198
Escriba-Aguir V, Perez-Hoyos S, Saurel-Cubizolles MJ (2001) Physical load and psychological demand at work during pregnancy and preterm birth. Int Arch Occup Environ Health 74(8):583–588
Fortier I, Marcoux S, Brisson J (1995) Maternal work during pregnancy and its risks of delivering a small-for-gestational-age or preterm infant. Scand J Work Environ Health 21:412–418
Hanke W, Jurewicz J (2004) The risk of adverse reproductive and developmental disorders due to occupational pesticide exposure—overview of current epidemiological evidence. Int J Occup Med Environ Health 17 (2):223–243
Hanke W, Kalinka J, Makowiec-Dąbrowska T, Sobala W (1999) Heavy physical work during pregnancy—a risk factor for small-for-gestational-age babies in Poland. Am J Ind Med 36(1):200–205
Hanke W, Romitti P, Fuortes L, Sobala W, Mikulski M (2003) The use of pesticides in Polish rural population and its effect on birth weight. Int Arch Occup Environ Health 76:614–620
Hemminki K, Mutanen P, Luoma K, Saloniemi I (1980) Congenital malformations by the parental occupation in Finland. Int Arch Occup Environ Health 46:93
Hernandez-Valero M, Bondy M, Spitz MR, Zahn SH (2001) Evaluation of Mexican American migrant farmworker work practices and organochlorine pesticide metabolities. Am J Ind Med 40:554–560
Homer CJ, Beresford SA, James SA, Siegel E, Wilcox S (1990) Work-related physical exertion and risk of preterm, low birthweight delivery. Paediatr Perinat Epidemiol 42:161–174
Koemeester AP, Broersen JP, Treffers PE (1995) Physical work load and gestational age at delivery. Occup Environ Med 52(5):313–315
Makowiec-Dąbrowska , Hanke W, Radwan-Włodarczyk Z, Koszada-Włodarczyk W, Sobala W (2003) Working conditions of pregnant women Departure from the regulations on occupations particularly noxious or hazardous to women (in Polish). Med Pr 54(1):33–43
Makowiec-Dąbrowska T, Siedlecka J (1996) Physical exertion at work and the course and outcome of pregnancy (in Polish). Med Pr 47(6):629–649
Morris N, Osborn SB, Wright HP, Hart A (1956) Effective uterine blood flow during exercise in normal and pre-eclamptic pregnancies. Lancet ii:481–484
Mozurkewich EL, Luke B, Avni M, Wolf FM (2000) Working conditions and adverse pregnancy outcome: a meta-analysis. Obstet Gynecol 95(4):623–635
Nurminen T, Lusa S, Ilmarinen J, Kruppa K (1989) Physical workload, fetal development and course of pregnancy. Scand J Work Environ Health 15:404–414
Nurminen T (1995) Maternal pesticide exposure and pregnancy outcome. JOEM 37(8):935–940
Orme S, Kegley S (2000–2004) PAN Pesticide Database, Pesticide Action Network, North America; http:www.pesticideinfo.org
Ratcliffe JM, Schrader SM, Steenland K, ClappDE, Turner T, Hornung RW (1987) Semen quality in papaya workers with long term exposure to ethylene dibromide. Br J Ind Med 44:317–326
Restrepo M, Munoz N, Day EN, Parra JE, Romero L, Nguyen-Dinh X (1990) Prevalence of adverse reproductive outcomes in a population occupationally exposed to pesticides in Columbia. Scand J Work Environ Health 16:232–238
Sallmén M, Liesivuori J, Taskinen H, Lindbohm M-L, Anttila A, Alto L, et al (2003) Time to pregnancy among wives of Finnish greenhouse workers. Scand J Work Environ Health 29(2):85–93
Spinillo A, Capuzzo E, Baltaro F, Piazza G, Nicola S, Iasci A (1996) The effect of work activity in pregnancy on the risk of fetal growth retardation. Acta Obstet Gynecol Scand 75(6):531–536
Waiter L, Rochardson S, H–mon D (1997) Accounting for pregnancy dependence in epidemiological studies of reproductive outcomes. Epidemiol 8(6):629–636
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Jurewicz, J., Hanke, W., Makowiec-Dąbrowska, T. et al. Exposure to pesticides and heavy work in greenhouses during pregnancy: does it effect birth weight?. Int Arch Occup Environ Health 78, 418–426 (2005). https://doi.org/10.1007/s00420-005-0614-x
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DOI: https://doi.org/10.1007/s00420-005-0614-x