Summary
A total of 31 pediatric cardiac patients (mean age 19 ½ months) who required surgery for repair of various congenital heart defects were prospectively studied in the postoperative period to determine potassium (K) dose-response characteristics. All patients received supplementary K when the serum K was <4.0 meq/liter. A total of 100 administrations of intravenous potassium chloride (KCl) were evaluated. KCl, 0.5 meq/kg, was infused over 2 h by syringe pump. This infusion was repeated as necessary to achieve a serum K≥4.0 meq/liter. The KCl was administered in addition to the K in the patients' maintenance solution. Blood samples for serum K determination were collected 15–30 min before and after the KCl infusion. The mean K dose administered was 0.72±0.23 meq/kg. This produced a mean rise in serum K of 0.61±0.48 meq/liter. Of 100 administrations, 11 resulted in no change or a decrease in serum K. Four of 100 administrations resulted in serum K>5.0 meq/liter. Intravenous KCl supplementation in a dose of 0.5 meq/kg administered over 2 h is safe and effective for pediatric postoperative cardiac patients. Serum K should be measured to monitor therapy, due to variable response.
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References
Breckenridge IM, Deverall PB, Kirklin JW, Digerness SB (1972) Potassium intake and balance after open intracardiac operations.J Thorac Cardiovasc Surg 63:305
Manning SH, Angaran DM, Arom KV, Lindsay WG, Northrup WF III, Nicoloff DM (1982) Intermittent intravenous potassium therapy in cardiopulmonary bypass patients.Clin Pharm 1:234
Schultze RG (1973) Recent advances in the physiology and pathophysiology of potassium excretion.Arch Intern Med 131:885
Sterns RH, Cox M, Feig PU, Singer I (1981) Internal potassium balance and the control of the plasma potassium concentration.Medicine 60:339
Weidner NJ, Gaum WE, Chou TC, Kaplan S (1978) Hyperkalemia-electrocardiographic abnormalities.J Pediatr 93:462
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Schaber, D.E., Uden, D.L., Stone, F.M. et al. Intravenous KCl supplementation in pediatric cardiac surgical patients. Pediatr Cardiol 6, 25–28 (1985). https://doi.org/10.1007/BF02265404
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DOI: https://doi.org/10.1007/BF02265404