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Interpretation of quality of life changes

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Abstract

The clinical significance of quality of life changes has little to do with the QOL as a measure, but is rather a reflection on the novelty of the measures and researcher's inexperience in their use. This article discusses possible ways of evaluating quality of life measures in terms of patient-clinician interactions and how the clinician can assess the importance of these changes of QOL in terms of treatment and management of disease.

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References

  1. Testa MA. Interpreting quality-of-life clinical trial data for use in the clinical practice of antihypertensive therapy. J Hypertens 1987; 5(Suppl 1): S9-S13.

    Google Scholar 

  2. Ware JEJr, Manning WGJr, Duan N, Wells KB, Newhouse JP. Health status and the use of outpatient mental health services. Am Psychol 1984; 39: 1090–1100.

    Google Scholar 

  3. Salsburg DS, Turner RS. Defining clinical meaningful units of change for health outcome research. Quality of Life Newsletter 1992; 3: 1.

    Google Scholar 

  4. Sackett DL, Haynes RB, Tugwell P. Clinical epidemiology: a basic science for clinical medicine. Boston/Toronto: Little, Brown & Co, 1985: 181–182.

    Google Scholar 

  5. Jacobson NS, Truax P. Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. J Consult Clin Psychol 1991; 59: 12–19.

    Google Scholar 

  6. Jaeschke R, Singer J, Guyatt GH. Measurement of health status: Ascertaining the minimal clinically important difference. Control Clin Trial 1989; 10: 407–415.

    Google Scholar 

  7. Gormley GJ, Stoner E, Bruskewitz RC, et al. The effect of finasteride in men with benign prostatic hyperplasia. N Engl J Med 1992; 327: 1185–1191.

    Google Scholar 

  8. Girman CJ, Panser LA, Chute CG, et al. Natural history of prostatism: Urinary flow rates in a community-based study. J Urology (in press).

  9. Kazis LE, Anderson JJ, Meenan RF. Effect sizes for interpreting changes in health status. Med Care 1989; 27: S178-S189.

    Google Scholar 

  10. Testa MA, Lenderking WR. Interpreting pharmacoeconomic and quality-of-life clinical trial data for use in therapeutics. PharmacoEconomics 1992; 2: 107–117.

    Google Scholar 

  11. Brook RH, Ware JEJr, Rogers WH, et al. Does free care improve adults' health? Results from a randomized controlled trial. N Engl J Med 1983; 309: 1426–1434.

    Google Scholar 

  12. Cleeland CS. Assessment of pain in cancer measurement issues. Adv Pain Res Ther 1990; 16: 47–55.

    Google Scholar 

  13. Spitz PW, Fries JF. The present and future comprehensive outcome measures for rheumatic diseases. Clin Rheumatol 1987; 6(Suppl 2): 105–11.

    Google Scholar 

  14. Marder SR, Mintz J, VanPutten R, Lebell M, Wirshing WC, Johnston-Cronk K. Early prediction of relapse in schizophrenia: an application of receiver operating characteristics (ROC) methods. Psychopharmacol Bull 1991; 27: 79–82.

    Google Scholar 

  15. Deyo RA, Inui TS. Toward clinical applications of health status measures: sensitivity of scales to clinical important changes. Health Svcs Res 1984; 19: 275–289.

    Google Scholar 

  16. Guyatt G, Walter S, Norman G. Measuring change over time: Assessing the usefulness of evaluative instruments. J Chron Dis 1987; 40: 171–178.

    Google Scholar 

  17. Fletcher A, Gore S, Jones D, Fitzpatrick R, Spiegelhalter D, Cox D. Quality of life measures in health care. II. Design, analysis, and interpretation. Br Med J 1992; 305: 1145–1148.

    Google Scholar 

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Lydick, E., Epstein, R.S. Interpretation of quality of life changes. Qual Life Res 2, 221–226 (1993). https://doi.org/10.1007/BF00435226

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