Table 5

Haplotype analysis of COMT and DRD2 variants on other neurobehavioural traits in the NFBC1966

Gene	Variant	Group	Gender	HSCL (total)		HSCL (depression)		HSCL (anxiety)		Depression diagnosis		Harm avoidance
Gene	Variant	Group	Gender	β	p Value	β	p Value	β	p Value	OR	p Value	β	p Value
COMT	rs737866	High risk	Males	0.0640	0.0254	0.0440	0.2239	0.0150	0.6157	0.7130	0.5004	0.7820	0.3799
COMT	rs5993883-rs2239393 (CG)	High risk	Males	0.0830	0.0040	0.0750	0.0176	0.0200	0.2877	0.2100	0.1506	1.2040	0.1433
DRD2	rs4648318-rs4274224 (GG)	All	Males	0.0694	0.00005	0.0600	0.0015	0.0326	0.0212	0.8280	0.6798	1.0430	0.07009

Empirical p values based on permutation are reported, with p values <0.05 shown in bold.
HSCL, Hopkins Symptom Check List.