Gene | Variant | Haplotype | Frequency | Males and females | Males | ||
β | p Value | β | p Value | ||||
DRD2 | 2-SNP haplotype analysis | ||||||
rs4648318–rs4274224 | GG | 0.05 | 0.0409 | 0.0007 | 0.0694 | 0.00005 | |
rs4274224–rs4581480 | GG | 0.07 | 0.0220 | 0.0069 | 0.0321 | 0.0023 | |
AA | 0.48 | 0.0116 | 0.0161 | −0.0237 | 0.0004 | ||
rs4581480–rs7131056 | GA | 0.07 | 0.0220 | 0.0071 | 0.0322 | 0.0026 | |
3-SNP haplotype analysis | |||||||
rs4648318–rs4274224–rs4581480 | GGG | 0.05 | 0.0326 | 0.0027 | 0.0437 | 0.0019 | |
rs4274224–rs4581480–rs7131056 | GGA | 0.07 | 0.0215 | 0.0081 | 0.0317 | 0.0033 |
Empirical p values based on permutation are reported, with p values <0.05 shown in bold.