Top 20 pathways associated with the 229 in silico replicated differentially expressed genes
| Pathway | No of differentially expressed genes in the pathway/total no of genes in the pathway | Fisher exact test p value |
| Glucocorticoid receptor signalling | 30/250 | 2.1E–16 |
| IL-6 signalling | 15/88 | 6.0E–11 |
| Hepatic fibrosis/hepatic stellate cell activation | 16/116 | 3.6E–10 |
| Molecular mechanisms of cancer | 24/303 | 1.8E–09 |
| IL-17 signalling | 12/70 | 4.9E–09 |
| Pancreatic adenocarcinoma signalling | 14/102 | 5.1E–09 |
| Nuclear factor (NF)-κβ signalling | 16/154 | 2.4E–08 |
| IL-10 signalling | 11/65 | 2.5E–08 |
| Peroxisome Proliferator-Activated Receptor (PPAR) signalling | 12/81 | 2.7E–08 |
| Role of osteoblasts, osteoclasts and chondrocytes in rheumatoid arthritis | 17/189 | 7.5E–08 |
| Germ cell–Sertoli cell junction signalling | 14/138 | 2.5E–07 |
| Dendritic cell maturation | 14/139 | 2.7E–07 |
| Apoptosis signalling | 11/86 | 4.9E–07 |
| p38 Mitogen-Activated Protein Kinase (MAPK) signalling | 11/89 | 6.9E–07 |
| Colorectal cancer metastasis signalling | 16/206 | 1.3E–06 |
| Atherosclerosis signalling | 10/77 | 1.4E–06 |
| Tumor Necrosis Factor Receptor 1 (TNFR1) signalling | 8/45 | 1.4E–06 |
| Regulation of IL-2 Expression in activated and anergic T lymphocytes | 10/79 | 1.8E–06 |
| Peroxisome Proliferator-Activated Receptor Alpha (PPARα)/Retinoid X Receptor Alpha (RXRα) activation | 13/142 | 2.2E–06 |
| IL-4 signalling | 9/64 | 2.4E–06 |
IL, interleukin.