Cells | Platform | No of cases (females/males) | No of controls (females/males) | Mean age (cases/controls) | No of reported differentially expressed genes with a Human Gene Nomenclature symbol | Original publication |
PBMC | U95Av2 array (Affymetrix, California). Represents approximately 10 000 genes. | 26 (20/6) | 18 (16/2) | 41/39.6 | 34 | Achiron et al10 |
Whole blood | 10.5 K Peter MacCallum array (The Peter MacCallum Cancer Institute, Australia). Represents 9381 unique cDNAs. | 20 (11/9) | Pooled sample (20/0); five individual samples (0/5) | Not provided (range 30–66 in MS, 20–55 in controls) | 2217 | Arthur et al11 |
PBMC | cDNA arrays with 6500 or 7500 clones with partial overlap | 24 (15/9) | 19 (5/14) | 42/37.5 (age for four controls unknown) | 104 | Bomprezzi et al12 |
Whole blood | HT-12 array (Illumina, California). Represents 48 804 transcripts. | 99 (66/33) | 45 (29/16) | 54/48.5 | 779 | Gandhi et al9 |
PBMC | U95Av2 array (Affymetrix, California). Represents approximately 10 000 genes. | 13 (9/4) | 5 (4/1) systematic lupus erythematosus (SLE), 10 healthy controls (16/2) | 40.7/42.8 (SLE)/39.6 | 78 | Mandel et al13 |
PBMC (monocytes depleted) | GeneFilters GF211 DNA array (Research Genetics, Alabama). Represents 5184 genes. | 15 (11/4) | 15 (gender matched to cases, but numbers not available) | 42.1/41.7 | 28 | Ramanathan et al14 |
T cells, non-T cells | A custom array with 1258 cDNAs (Hitachi Life Science, Saitama, Japan) | 72 (55/18) | 22 (16/6) | 36.1/38.6 | 185 | Satoh et al15 |
T cells | A custom array with 1258 cDNAs (Hitachi Life Science, Saitama, Japan) | 72 (55/18) | 22 (16/6) | 36.1/38.6 | 281 | Satoh et al16 |
PBMC, peripheral blood mononuclear cell.