Table 1

Description of previous microarray expression studies included in the systematic review

CellsPlatformNo of cases (females/males)No of controls (females/males)Mean age (cases/controls)No of reported differentially expressed genes with a Human Gene Nomenclature symbolOriginal publication
PBMCU95Av2 array (Affymetrix, California). Represents approximately 10 000 genes.26 (20/6)18 (16/2)41/39.634Achiron et al10
Whole blood10.5 K Peter MacCallum array (The Peter MacCallum Cancer Institute, Australia). Represents 9381 unique cDNAs.20 (11/9)Pooled sample (20/0); five individual samples (0/5)Not provided (range 30–66 in MS, 20–55 in controls)2217Arthur et al11
PBMCcDNA arrays with 6500 or 7500 clones with partial overlap24 (15/9)19 (5/14)42/37.5 (age for four controls unknown)104Bomprezzi et al12
Whole bloodHT-12 array (Illumina, California). Represents 48 804 transcripts.99 (66/33)45 (29/16)54/48.5779Gandhi et al9
PBMCU95Av2 array (Affymetrix, California). Represents approximately 10 000 genes.13 (9/4)5 (4/1) systematic lupus erythematosus (SLE), 10 healthy controls (16/2)40.7/42.8 (SLE)/39.678Mandel et al13
PBMC (monocytes depleted)GeneFilters GF211 DNA array (Research Genetics, Alabama). Represents 5184 genes.15 (11/4)15 (gender matched to cases, but numbers not available)42.1/41.728Ramanathan et al14
T cells, non-T cellsA custom array with 1258 cDNAs (Hitachi Life Science, Saitama, Japan)72 (55/18)22 (16/6)36.1/38.6185Satoh et al15
T cellsA custom array with 1258 cDNAs (Hitachi Life Science, Saitama, Japan)72 (55/18)22 (16/6)36.1/38.6281Satoh et al16
  • PBMC, peripheral blood mononuclear cell.