Characteristics of study population
| Variables | Low short-term/low lifetime risk (N*=3983, 1980, 2003) | Low short-term/high lifetime risk (N*=3706, 2358, 1348) | High short-term risk (N*=2365, 1969, 396) |
| Age, years; mean (SD) | 35.8 (10.4) | 39.8 (9.4) | 50.6 (7.0) |
| Men | 36.7 (11.0) | 39.0 (9.3) | 50.8 (6.5) |
| Women | 34.9 (9.8) | 41.2 (9.5) | 50.0 (9.2) |
| Systolic blood pressure, mm Hg; mean (SD) | 117.0 (10.7) | 126.6 (16.3) | 136.3 (19.6) |
| Men | 119.5 (9.8) | 125.7 (15.0) | 135.7 (19.0) |
| Women | 114.6 (11.0) | 128.2 (18.2) | 139.7 (22.1) |
| Diastolic blood pressure, mm Hg; mean (SD) | 74.0 (8.1) | 80.0 (11.5) | 83.3 (11.1) |
| Men | 74.5 (7.9) | 79.3 (11.2) | 83.0 (11.1) |
| Women | 73.5 (8.4) | 81.2 (11.9) | 84.9 (10.7) |
| Body mass index, kg/m2; mean (SD) | 23.4 (4.0) | 23.7 (4.4) | 24.6 (3.8) |
| Men | 23.0 (3.5) | 23.2 (3.8) | 24.4 (3.5) |
| Women | 23.7 (4.4) | 24.5 (5.1) | 25.9 (4.9) |
| Waist circumference, cm; mean (SD) | 82.0 (11.4) | 83.9 (11.3) | 89.4 (10.0) |
| Men | 84.6 (10.4) | 85.1 (10.5) | 89.9 (9.6) |
| Women | 79.3 (11.7) | 81.8 (12.4) | 87.0 (11.4) |
| Plasma glucose, mg/dl; mean (SD) | 86.9 (13.0) | 89.0 (13.8) | 116.2 (46.2) |
| Men | 88.1 (13.1) | 89.1 (14.0) | 111.9 (41.3) |
| Women | 85.6 (12.8) | 88.9 (13.5) | 137.6 (61.2) |
| Total cholesterol, mg/dl; mean (SD) | 158.8 (24.9) | 184.3 (44.3) | 194.1 (42.3) |
| Men | 159.1 (25.3) | 178.9 (43.4) | 193.0 (41.1) |
| Women | 158.5 (24.5) | 193.9 (44.2) | 199.6 (47.4) |
| High-density lipoprotein, mg/dl; mean (SD) | 43.1 (10.1) | 46.0 (11.0) | 39.6 (10.1) |
| Men | 41.6 (9.7) | 45.3 (10.9) | 39.0 (9.4) |
| Women | 44.6 (10.4) | 47.2 (11.1) | 42.8 (12.2) |
| Triglycerides, mg/dl; mean (SD) | 108.7 (50.7) | 129.7 (71.3) | 160.6 (94.4) |
| Men | 118.0 (55.9) | 133.5 (73.6) | 161.5 (94.8) |
| Women | 99.5 (42.9) | 123.0 (66.5) | 156.1 (92.1) |
| Total cholesterol/high-density lipoprotein; mean (SD) | 3.9 (1.0) | 4.2 (1.4) | 5.2 (1.7) |
| Men | 4.0 (1.0) | 4.1 (1.4) | 5.2 (1.6) |
| Women | 3.7 (1.0) | 4.3 (1.4) | 5.0 (1.9) |
| Current tobacco use (n, %) | 0 | 1592, 43.0 | 1114, 47.0 |
| Men | 0 | 1310, 55.6 | 1054, 53.5 |
| Women | 0 | 282, 20.9 | 58, 14.6 |
| Diabetes (n, %) | 0 | 0 | 952, 40.3 |
| Men | 0 | 0 | 664, 33.7 |
| Women | 0 | 0 | 288, 72.7 |
| Hypertension (n, %) | 0 | 1403, 37.9 | 1251, 53.1 |
| Men | 0 | 793, 33.6 | 994, 50.5 |
| Women | 0 | 610, 45.3 | 261, 65.9 |
| Dyslipidaemia (n, %) | 501, 12.6 | 904, 24.4 | 1153, 48.8 |
| Men | 294, 14.8 | 554, 23.5 | 977, 49.6 |
| Women | 207, 10.3 | 350, 26.0 | 176, 44.4 |
| Antihypertensive therapy (n, %) | 0 | 298, 8.0 | 444, 18.8 |
| Men | 0 | 154, 6.5 | 338, 17.2 |
| Women | 0 | 144, 10.7 | 106, 26.8 |
| Framingham 10 year risk, % (median and IQR) | 0.8 (0.1–2.9) | 3.6 (1.3–6.4) | 13.1 (10.7–16.7) |
| Men | 1.8 (0.4–4.8) | 4.4 (1.8–7.0) | 13.5 (11.1–17.2) |
| Women | 0.2 (0.0–1.4) | 2.3 (0.5–4.8) | 11.2 (7.0–14.4) |
↵* N for total, men and women.