Screening performance of various 60 min observation algorithms for the prediction of pre-eclampsia or related complications (including PIH and eclampsia) where childbirth occurred within 1 week of PDAC attendance
| Criteria for screen positivity at 60 min | Screen positive rate (%) | Sensitivity (%) | Specificity (%) | Positive LR* (95% CI) | Negative LR* (95% CI) | False-negative rate (%) |
|---|---|---|---|---|---|---|
| 1 or more high BP and symptoms | 31.3 | 32.3 | 92.9 | 5.1 E (1.3 to 19.7) | 0.7 P (0.6 to 0.8) | 67.7 |
| 1 or more high BP and abnormal lab Ix | 54.6 | 59.3 | 73.1 | 1.8 P (1.1 to 3.2) | 0.6 P (0.5 to 0.8) | 40.7 |
| 2 or more high BP, or 1 high BP with either symptoms, lab Ix abnormal or both | 77.9 | 83.7 | 50.0 | 1.7 P (1.1 to 2.4) | 0.3 P (0.2 to 0.5) | 16.4 |
*Grading of clinical utility of likelihood ratios as per Mahutte and Duleba:15 E excellent, G good, P poor. BP, blood pressure; lab Ix, laboratory investigations; negative LR, negative likelihood ratio=(1-sensitivity)/specificity; PDAC, Pregnancy Day Assessment Clinic; PIH, pregnancy-induced hypertension; positive LR, positive likelihood ratio=sensitivity/(1−specificity).