Table 2

Apgar score (≤7) in AED exposed and unexposed children (monotherapy and polytherapy combined)

AED exposureN (%)Apgar score ≤7, n (%)Apgar score >7, n (%)Relative risk crude, (95% CI)Relative risk, adjusted* (95% CI)
Yes2906 (100)55 (1.9)2851 (98.1)1.45 (1.12 to 1.88)1.41 (1.07 to 1.85)
No674 115 (100)8797 (1.3)665 318 (98.7)1.00 (reference)1.00 (reference)
  • *Apgar score was adjusted for maternal age and smoking.

  • AED, antiepileptic drug.