Comparison of alcohol use in SCOPE Centre's
| Total n=5573 | New Zealand n=2006 | Ireland n=1766 | Australia n=1150 | UK* n=651 | p Value | |
|---|---|---|---|---|---|---|
| Pre-pregnancy alcohol consumption | 4319 (77) | 1552 (77) | 1586 (90) | 539 (53) | 540 (83) | <0.001 |
| Non-drinkers pre-pregnancy | 1254 (23) | 454 (23) | 180 (10) | 611 (47) | 111 (17) | |
| Severity of consumption (units/week)† | ||||||
| 1–2 | 1126 (26) | 503 (32) | 287 (18) | 232 (38) | 104 (19) | <0.001 |
| 3–7 | 1674 (39) | 698 (45) | 602 (38) | 211 (34) | 163 (30) | |
| 8–14 | 963 (22) | 253 (16) | 451 (28) | 94 (15) | 165 (31) | |
| >14 | 528 (12) | 98 (6) | 246 (16) | 76 (12) | 108 (20) | |
| Median (IQR) | 5 (2, 10) | 4 (2, 7) | 6 (3, 11) | 4 (1, 8) | 7.5 (3, 13) | <0.001 |
| Pre-pregnancy binging | 1741 (31) | 337 (17) | 1044 (59) | 123 (11) | 247 (38) | <0.001 |
| Any alcohol in pregnancy | 3482 (63) | 1107 (56) | 1444 (82) | 459 (40) | 476 (75) | <0.001 |
| Non-drinkers in pregnancy | 2091 (37) | 899 (44) | 322 (18) | 691 (60) | 175 (25) | |
| Binge (any in pregnancy) | 1282 (23) | 167 (9) | 795 (45) | 113 (10) | 207 (33) | <0.001 |
| First trimester alcohol consumption | 3370 (60) | 1063 (53) | 1415 (80) | 440 (38) | 451 (69) | <0.001 |
| Non-drinking in first trimester | 2203 (40) | 943 (47) | 171 (20) | 710 (62) | 200 (61) | |
| Severity of consumption (units/week)† | ||||||
| 1–2 | 1078 (32) | 361 (34) | 424 (30) | 142 (32) | 151 (34) | <0.001 |
| 3–7 | 1372 (41) | 463 (44) | 600 (42) | 158 (36) | 151 (34) | |
| 8–14 | 624 (19) | 175 (16) | 266 (19) | 80 (18) | 103 (23) | |
| >14 | 296 (9) | 65 (6) | 125 (9) | 60 (14) | 46 (10) | |
| Binge first trimester | 1279 (23) | 167 (8) | 795 (45) | 111 (10) | 206 (32) | <0.001 |
| Median (IQR) | 4 (2, 8) | 4 (2, 7) | 4 (2, 7.5) | 5 (2, 10) | 4 (1.9, 9) | 0.020 |
| Second trimester alcohol consumption | 1018 (19) | 232 (12) | 500 (29) | 73 (7) | 213 (34) | <0.001 |
| Non-drinking in second trimester | 4555 (81) | 1774 (88) | 1266 (71) | 1077 (83) | 438 (66) | |
| Severity of consumption (units/week)† | ||||||
| 1–2 | 976 (97) | 220 (97) | 486 (98) | 68 (93) | 202 (96) | 0.3 |
| 3–7 | 30 (3) | 7 (3) | 11 (2) | 4 (5) | 8 (4) | |
| 8–14 | 3 (0.3) | 0 | 1 (0.2) | 1 (1) | 1 (0.5) | |
| >14 | 0 | 0 | 0 | 0 | 0 | |
| Binge second trimester | 18 (0.4) | 2 (0.1) | 7 (0.4) | 6 (1) | 3 (1) | 0.2 |
| Median (IQR) | 0.5 (0.3, 1) | 0.5 (0.3, 1) | 0.5 (0.3, 1) | 0.5 (0.1, 1) | 0.8 (0.5, 1.5) | <0.001 |
All data are N (%) unless otherwise stated. Median difference between centres tested using Kruskall-Wallis test. All other differences tested with χ2 test for categorical variables.
*London, Manchester, Leeds.
†Note that severity of alcohol consumption only refers to women who consumed alcohol during pregnancy.
IQR, interquartile range; SCOPE, Screening for Pregnancy Endpoints.