Table 3

Model estimates

ParameterValueAbsolute numbersDifference
No vaccination
 Working mothers with a 1st child75
 % of mothers with a 1st child having diarrhoea 1st year20%75×20%=15
 Average duration (days) for being absent for diarrhoea in a child515×5=75
 Average number of days absent/woman75/75=11
Vaccination
 Working mothers with a 1st child75
 % of mothers with a vaccinated child85%75×85%=64
 % of mothers with no vaccinated child(1–85%)=15%75×15%=11
 Vaccine efficacy against diarrhoea85%
 % of mothers with a vaccinated child still having diarrhoea20%×(100%–85%)=3%64×3%=2
 % of mothers with an unvaccinated child still having diarrhoea (Rest)20%11×20%=2
 Average duration (days) for being absent for diarrhoea in a child54×5=20
 Average number of days absent/woman20/75=0.270.27
 Gain in working days avoided/woman after vaccination 1st year(1–0.27)=0.73
Sensitivity analysis
 Proportion of children with diarrhoea is lower because of the vaccine's herd effect in the Rest group10% instead 20%11×10%=1
 Average duration (days) for being absent for diarrhoea in a child3×5=15
 Average number of days absent/woman15/75=0.200.20
 Gain in working days avoided/woman after vaccination 1st year(1–0.20)=0.80