INR time and value in therapeutic range
| Study ID | INR time in therapeutic range, mean % (SD) | INR value in target range, % of INR values (95% CI) | ||||
|---|---|---|---|---|---|---|
| PSM/PST | Control | p Value | PSM/PST | Control | p Value | |
| Azarnoush et al 201156 | 61.5 (19.3) | 55.5 (19.9) | 0.0343 | NR | NR | NR |
| Bauman et al 201063 | PSM: 83 (NR) PST: 83.9 (NR) | – | NR | NR | NR | NR |
| Christensen et al 200639 | 78.7 (69.2–81.0)* | 68.9 (59.3–78.2)* | 0.14 | NR | NR | NR |
| Christensen 201157 | 80.2 (2.3) | 72.7 (2.6) | <0.001 | 80.8 (79.3–82.1) | 67.2 (64.1–70.2) | <0.001 |
| Cromheecke et al 200040 | NR | NR | NS | 55 (NR) | 49 (NR) | 0.06 |
| Eitz et al 200841 | NR | NR | 79 (NR) | 65 (NR) | <0.001 | |
| Fitzmaurice et al 200242 | 74 (16.2) | 77 (23.5) | NS | 66 (61–71) | 72 (65–80) | NS |
| Fitzmaurice et al 200543 | 70 (20.1) | 68 (23.0) | 0.18 | 70 (64.8–74.8)† | 72 (66.3 to 77.1)† | NS |
| Gadisseur et al 200362 | PSM: 68.6 (16.8) PST: 66.9 (14.9) | 67.9 (19.5) | 0.33 | 66.3 (61–71.5)/ 63.9 (59.8–68)‡ | 61.3 (55–62.4)/58.7‡ | 0.14 |
| Gardiner et al 200664 | PSM: 69.9 (23.1) PST: 71.8 (22.1) | – | 0.46 | NR | NR | NR |
| Horstkotte et al 199645 | NR | NR | 43.2 (NR) | 22.3 (NR) | <0.001 | |
| Khan et al 200459 | 71.1 (14.5) | 70.4 (24.5) | NS | NR | NR | NR |
| Kortke et al 200146 | NR | NR | NR | 79.2 (NR) | 64.9 (NR) | <0.001 |
| Matchar et al 201060 | 66.2 (14.2) | 62.4 (17.1) | <0.001 | NR | NR | NR |
| Menendez-Jandula et al 200547 | 64.3 (14.3) | 64.9 (19.9) | 0.2 | 58.6 (SD 14.3)† | 55.6 (SD 19.6)† | 0.02 |
| Rasmussen et al 201248 | 52 (33–65)§ | 55 (49–66) | NR | NR | NR | NR |
| Ryan et al 200961 | 74 (64.6–81)¶ | 58.6 (45.6–73.1)¶ | <0.001 | NR | NR | NR |
| Sawicki 199949 | NR | NR | NR | 53 (NR)† | 43.2 (NR)† | 0.22 |
| Sidhu and O'Kane 200150 | 76.5 (NR) | 63.8 (NR) | <0.0001 | NR | NR | NR |
| Siebenhofer et al 200851 | 75.4 (9.4, 85.0)¶ | 66.5 (47.1, 81.5)¶ | <0.001 | NR | NR | NR |
| Soliman Hamad et al 200952 | NR | NR | NR | 72.9 (SD 11)† | 53.9 (SD 14)† | 0.01 |
| Sunderji et al 200453 | 71.8 (45.69) | 63.2 (48.53) | 0.14 | NR | NR | NR |
| Verret et al 201254 | 80 (13.5) | 75.5 (24.7) | 0.79 | NR | NR | NR |
| Völler et al 200555 | 178.8 (126)** | 155.9 (118.4)** | NS | 67.8 (SD 17.6) | 58.5 (SD 19.8) | 0.0061 |
*Median % (95% CI).
†mean % of individual (95% CI).
‡% (95% CI).
§Median % (25–75 centile).
¶Median % (IQR).
**Mean cumulative days (SD).
INR, international normalised ratio; PSM, patient self-management; PST, patient self-testing; NR, not reported; NS, not significant.