Genotypic and allelic frequency distribution of −384A/C and 584C/T Polymorphic of LIPG gene in female patients and female controls with CAD
| CAD n=83 | Control n=134 | p Value* | OR (95% CI) | ||
|---|---|---|---|---|---|
| −384A/C | |||||
| Genotype frequency | AA | 59 (71.1%) | 103 (76.9%) | Reference | |
| AC | 19 (22.9%) | 29 (21.6%) | |||
| CC | 5 (6.0%) | 2 (1.5%) | 0.184 | ||
| AC+CC | 24 (28.9%) | 31 (23.1%) | 0.341 | 1.352 (0.726 to 2.516) | |
| Allele frequency | A | 137 (82.5%) | 235 (87.7%) | Reference | |
| C | 29 (17.5%) | 33 (12.3%) | 0.136 | 1.507 (0.877 to 2.591) | |
| 584C/T | |||||
| Genotype frequency | CC | 46 (55.4%) | 89 (66.4%) | Reference | |
| CT | 37 (44.6%) | 41 (30.6%) | |||
| TT | 0 | 4 (3.0%) | 0.043 | ||
| CT+TT | 37 (44.6%) | 45 (33.6%) | 0.104 | 1.591 (0.907 to 2.791) | |
| Allele frequency | C | 129 (77.7%) | 219 (81.7%) | Reference | |
| T | 37 (22.3%) | 49 (18.3%) | 0.309 | 1.282 (0.794 to 2.070) | |
*Compared with controls.
CAD, coronary artery disease; LIPG, endothelial lipase gene.