Estimated parameters from growth curve analysis of continuous outcomes
| Effect sizes (Cohen's d) with 95% CI | Rate of change | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Measure | Pre M (SD) | Post M (SD) | 6 MFU M (SD) | LFU M (SD) | Pre to post | Pre to 6 MFU | Pre to LFU | Pre to Post β 95% CI | Post to LFU β 95% CI |
| LSAS-SR | 69.07 (22.90) | 50.38 (24.37) | 46.13 (26.21) | 41.87 (24.24) | 0.79 [0.69 to 0.89] | 0.92 [0.75 to 1.09] | 1.17 [1.02 to 1.32] | −18.69*** [−20.63 to −16.74] | −4.26*** [−5.33 to −3.09] |
| MADRS-S | 14.57 (7.62) | 9.78 (8.03) | 9.63 (9.11) | 9.48 (7.97) | 0.61 [0.52 to 0.70] | 0.59 [0.42 to 0.75] | 0.67 [0.54 to 0.80] | −4.78*** [−5.45 to −4.12] | −0.15 [−0.59 to −0.28] |
| EQ-5D | 0.81 (0.13) | 0.82 (0.15) | 0.83 (0.18) | 0.85 (0.18) | −0.12 [−0.22 to 0.01] | −0.17 [−0.36 to 0.02] | −0.25 [−0.40 to −0.10] | 0.02* [0.00 to 0.03] | 0.01* [0.00 to 0.02] |
Observed means and SDs for pretreatment, and estimated means and observed SDs for post-treatment, 6-month follow-up and long-term follow-up are reported. For Cohen’s d, an effect size of 0.2 is considered to be a small effect, 0.5 a medium effect and >0.8 a large effect. For slope coefficients of rate of change, significant effects of time on outcome are denoted as ***p<0.001; **p<0.01 and *p<0.05.
6 MFU, 6 months after treatment; EQ-5D, health-related quality of life; LFU, long-term follow-up 1.2–4 years after treatment start; LSAS-SR, Liebowitz Social Anxiety Scale questionnaire Self-Report; M, mean; MADRS-S, Montgomery Åsberg Depression Rating Scale Self-report; Post, post-treatment; Pre, before treatment.