Additional analysis on incidence of HF in relation to sex-specific quartiles of blood cadmium among never smokers
| Quartiles of blood cadmium | |||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | P trend | |
| HF, n, per 1000 p-y | 8 (1.7) | 23 (2.7) | 9 (3.4) | 2 (6.0) | |
| HR (95% CI), model 1 | 1.00 | 3.05 (1.36 to 6.83) | 1.48 (0.57 to 3.82) | 2.23 (0.47 to 10.50) | 0.37 |
| HR (95% CI), model 2 | 1.00 | 3.72 (1.63 to 8.51) | 1.51 (0.56 to 4.03) | 2.87 (0.60 to 13.85) | 0.11 |
HR model 1 adjusted for age.
HR model 2 adjusted for age, systolic blood pressure, use of blood pressure-lowering or lipids-lowering medications, presence of diabetes mellitus, history of a coronary event, waist circumference, alcohol intake, LDL, HDL, hsCRP, plasma creatinine, marital and educational status.
HDL, high-density lipoprotein; HF, heart failure; hsCRP, high-sensitivity C reactive protein; LDL, low-density lipoprotein; p-y, person-year.