Table 3

Effect of patient information leaflets on antibiotic prescribing, antibiotic use, reconsultation and intention to reconsult in respiratory tract infections

AntibioticsReconsultation
Antibiotic prescribing
RR (95% CI)
Antibiotic use
RR (95% CI)
Reconsultation rate
RR (95% CI)
Intention to reconsult
RR (95% CI)
Agnew et al18
n=115
Respiratory tract infection
0.6 (0.42 to 0.86)
Everitt et al22
n=307
Acute conjunctivitis
0.86 (0.66 to 1.12)
Francis et al17
n=558
Respiratory tract infection
0.47 (0.36 to 0.64)0.53 (0.40 to 0.69)0.80 (0.52 to 1.21)*0.72 (0.63 to 0.82)
Little et al19
n=807
Respiratory tract infection
0.96 (0.83 to 1.11)1.53 (1.03 to 2.27)†
Macfarlane et al20
n=1014
Respiratory tract infection
1.15 (0.89 to 1.48)0.70 (0.53 to 0.91)†
Macfarlane et al21
n=259
Respiratory tract infection
0.76 (0.59 to 0.97)0.79 (0.38 to 1.67)†
  • Expressed as the risk of the outcome for those patients managed by patient leaflets compared with the risk of the outcome for patients managed in the control group (no leaflet).

  • *Within 2 weeks.

  • †Within 1 month.

  • RR, relative risk.