Treatment discontinuation due to adverse reactions
| Drug | Adverse reaction | Patients (N) |
|---|---|---|
| Valproic acid | Behavioural problems | 2 |
| Tiredness | 1 | |
| Nausea, vomiting, abdominal pain | 1 | |
| Hyperactivity, behavioural problems, tremor | 1 | |
| Mood swing | 1 | |
| Auditory hallucination | 1 | |
| Total | 7 | |
| Carbamazepine | Rash | 4 |
| Nausea ,vomiting, reduced appetite, incontinence, behavioural problems | 1 | |
| Gum hypertrophy | 1 | |
| Total | 6 | |
| Lamotrigine | Rash | 2 |
| Dizziness, sleep disturbance, abdominal pain | 1 | |
| Total | 3 | |
| Phenytoin | Steven-Johnson syndrome* | 1 |
| Dystonia, aggression, increased seizure | 1 | |
| Gum hypertrophy, drowsiness | 1 | |
| Total | 3 | |
| Phenobarbital | Steven-Johnson syndrome* | 1 |
| Levetiracetam | Nose bleed | 1 |
| Oxcarbazepine | Aggravated seizure | 1 |
| Paraldehyde | Respiratory arrest* | 1 |
| Total | 23 |
*Severe ADRs.
ADRs, adverse drug reactions.