Adverse event | Studies reporting, n | Patients reporting/total number | RR (95% CI) | p Value | p For heterogeneity | |
---|---|---|---|---|---|---|
Ibandronate | Zoledronate | |||||
Anorexia | 2 | 274/769 | 275/757 | 0.98 (0.86 to 1.12) | 0.77 | 0.29 |
Fatigue | 2 | 573/769 | 575/757 | 0.98 (0.93 to 1.04) | 0.56 | 0.41 |
Fever or influenza-like symptoms | 4 | 183/933 | 334/920 | 0.47 (0.22 to 1.01) | 0.05 | 0.002 |
Jaw osteonecrosis | 2 | 5/731 | 10/723 | 0.52 (0.19 to 1.44) | 0.21 | 0.75 |
Renal toxicity | 2 | 173/731 | 230/723 | 0.74 (0.63 to 0.88) | <0.001 | 0.29 |
[Bold] means p value served as the threshold for statistical significance.
RR, risk ratio.