Adverse event | Studies reporting, n | Patients reporting/total number | RR (95% CI) | p Value | p For heterogeneity | |
---|---|---|---|---|---|---|
Ibandronate | Placebo | |||||
Abdominal pain | 4 | 34/487 | 6/408 | 2.26 (1.09 to 4.70) | 0.03 | 0.36 |
Diarrhoea | 3 | 12/200 | 1/131 | 3.72 (0.96 to 14.38) | 0.06 | 0.40 |
Nausea | 2 | 24/375 | 6/297 | 2.05 (0.85 to 4.95) | 0.11 | 0.65 |
Renal toxicity | 2 | 20/595 | 15/435 | 1.14 (0.59 to 2.21) | 0.69 | 0.88 |
[Bold] means p value served as the threshold for statistical significance.
RR, risk ratio.