Table 2

Demographic data for included patients

CategoryGentamicin before (%)
n=195
Gentamicin after (%)
n=215
p ValueVancomycin before (%)
n=155
Vancomycin after (%)
n=142
p Value
Gender
 Male117 (60.0)97 (45.1)0.00387 (56.1)81 (57.0)0.907
 Female78 (40.0)118 (54.9)68 (43.9)61 (43.0)
Age±SD (years)55.4±17.357.6±18.50.21160.5±17.357.7±16.60.159
BMI±SD (kg/m2)25.8±6.026.2±6.00.54626.4±45.927.9±6.50.030
CrCl±SD (mL/min)97.3±51.790.6±48.20.17684.6±42.4100.7±43.00.001
Ethnicity
 White133 (68.2)144 (67.0)0.833100 (64.5)106 (74.6)0.060
 Black37 (19.0)49 (22.8)0.39630 (19.4)28 (19.7)1.000
 Asian10 (5.1)13 (6.0)0.8316 (3.9)5 (3.5)1.000
 Other7 (3.6)4 (1.9)0.3648 (5.2)2 (1.4)0.107
 Not specified8 (4.1)5 (2.3)0.40011 (7.1)1 (0.7)0.006
Specialty
 Haematology/oncology99 (50.8)55 (25.6)<0.00139 (25.2)16 (11.3)0.003
 Critical care45 (23.1)24 (11.2)0.00110 (6.5)3 (2.1)0.089
 Medicine16 (8.2)65 (30.2)<0.00144 (28.4)46 (32.4)0.528
 Surgery14 (7.2)27 (12.6)0.07322 (14.2)27 (19.0)0.277
 Liver8 (4.1)7 (3.3)0.79415 (9.7)13 (9.2)1.000
 Women/child6 (3.1)18 (8.4)0.0331 (0.6)2 (1.4)0.608
 Renal3 (1.5)1 (0.5)0.3500 (0)0 (0)
 Neuroscience3 (1.5)13 (6)0.02114 (9.0)25 (17.6)0.038
 Cardiology1 (0.5)5 (2.3)0.21910 (6.5)10 (7.0)1.000
  • BMI, body mass index; CrCl, creatinine clearance.