Clinical characteristics of patients with a rapid decline in renal function (>5 mL/min/1.73 m2/year)
| Rapid decline in eGFR (n=291) | No decline in eGFR (n=606) | p Value | |
|---|---|---|---|
| Age (years) | 72.1±8.4 | 71.6±9.3 | 0.486 |
| Body mass index (kg/m2) | 27.5±4.5 | 28.2±4.6 | 0.039 |
| Women (%) | 41.9 | 41.7 | 0.960 |
| Permanent AF (%) | 42.3 | 43.6 | 0.720 |
| Ankle-Brachial Index ≤0.90 (%) | 26.5 | 19.3 | 0.015 |
| Arterial hypertension (%) | 88.7 | 85.1 | 0.152 |
| Diabetes (%) | 23.0 | 24.6 | 0.608 |
| Heart failure (%) | 19.6 | 18.6 | 0.736 |
| History of stroke/TIA (%) | 10.0 | 11.9 | 0.396 |
| History of MI/CHD (%) | 19.6 | 17.8 | 0.523 |
| Antiplatelet (%) | 18.2 | 20.3 | 0.462 |
| ACE inhibitors/ARBs (%) | 69.4 | 74.4 | 0.068 |
| β blockers (%) | 51.5 | 47.2 | 0.222 |
| Calcium channel antagonists (%) | 27.8 | 26.9 | 0.768 |
| Statins (%) | 43.6 | 44.7 | 0.761 |
ACE, angiotensin converting enzyme; AF, atrial fibrillation; ARBs, angiotensin receptor blockers; CHD, coronary heart disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; TIA, transient ischaemic attack.