Table 1

Binary logistic regression analysis of factors associated with mood instability (n=27 704)

FactorGroupNumber in samplePrevalence of documented mood instability within 1 month (%)Association with mood instability
UnadjustedAdjusted model*
OR (95% CI)p ValueOR (95% CI)p Value
Age (years)16–25713316.31.28 (1.17 to 1.40)<0.0011.32 (1.20 to 1.45)<0.001
26–35784213.2ReferenceReference
36–4566119.80.71 (0.64 to 0.79)<0.0010.73 (0.65 to 0.81)<0.001
46–5540669.10.65 (0.58 to 0.74)<0.0010.67 (0.58 to 0.76)<0.001
56–6520527.10.50 (0.42 to 0.60)<0.0010.50 (0.41 to 0.60)<0.001
GenderMale12 53210.90.81 (0.75 to 0.87)<0.0010.75 (0.69 to 0.81)<0.001
Female15 17213.2ReferenceReference
EthnicityWhite15 69112.5ReferenceReference
Asian151112.61.01 (0.86 to 1.18)0.940.93 (0.79 to 1.09)0.36
Black520313.31.07 (0.98 to 1.18)0.150.95 (0.87 to 1.05)0.35
Other52999.80.76 (0.69 to 0.84)<0.0010.80 (0.72 to 0.89)<0.001
Marital status (first recorded)Married/cohabiting511511.70.88 (0.80 to 0.97)0.0101.16 (1.04 to 1.28)0.007
Divorced/separated239111.10.82 (0.72 to 0.94)0.0051.18 (1.02 to 1.36)0.028
Single16 07813.1ReferenceReference
Not recorded41209.40.69 (0.61 to 0.77)<0.0010.82 (0.73 to 0.92)0.001
DiagnosisSchizophrenia and related586015.52.11 (1.92 to 2.32)<0.0012.23 (2.02 to 2.46)<0.001
Bipolar affective disorder269122.63.37 (3.03 to 3.76)<0.0013.42 (3.06 to 3.82)<0.001
Psychotic depression76714.01.87 (1.51 to 2.31)<0.0012.00 (1.61 to 2.48)<0.001
Personality disorder231117.82.50 (2.21 to 2.82)<0.0012.39 (2.11 to 2.71)<0.001
Unipolar depression (without psychosis)14 1928.0ReferenceReference
Other affective disorder188310.61.36 (1.16 to 1.60)<0.0011.35 (1.15 to 1.59)<0.001
  • *Results adjusted for all the factors reported in this table.