Activity | Recruitment/ screening | Decision-making concerning IV thrombolysis | 24 h±3 h | 7 days ±1 day | At discharge | 1 month ±3 days | 3 months ±7 days |
---|---|---|---|---|---|---|---|
Enrolment | |||||||
Written informed consent | X | ||||||
Contact information | X | ||||||
Patient history | X | X | |||||
Time intervals* | X | X | |||||
Physical examination | X | ||||||
NIHSS | X | X | X | X | X | ||
Blood pressure | X | X | X | X | X | ||
CT scan | X | X | |||||
Blood glucose | X | X | |||||
Other laboratory tests | X | ||||||
Confirm eligibility | X | ||||||
Interventions | |||||||
IV thrombolysis | Eligible patients | ||||||
Supportive care | X | X | X | X | X | ||
Prevention/treatment of acute complications | X | X | X | X | X | ||
Assessments | |||||||
Stroke complications | X | X | X | ||||
New cardiovascular events | X | X | X | ||||
Length of hospitalisation | X | ||||||
mRS | X | X | X | X | |||
Death | X | X | X | X |
*Time intervals include that from stroke onset to arrival in the ED, and from arrival in the ED to physician/CT initiation/CT interpretation/specific treatment.
ED, emergency department; IV, intravenous; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.