Table 1

Characteristics of patients administered a 25 versus 50 mg dose of rectal diclofenac after ERCP

Rectal diclofenac
Total25 mg50 mgp Value
Men, % (n/N)54.8(85/155)46.4(39/84)64.8(46/71)0.022
Age (years), median (IQR)71.0 (63.0–76.0)73.5 (68.0–80.0)67.0 (57.0–74.0)<0.001
 Elderly aged ≥65, % (n/N)71.0(110/155)82.1(69/84)57.7(41/71)0.001
BMI (kg/m2), median (IQR)22.5 (19.5–25.3)23.2 (21.2–25.6)21.9 (19.2–24.4)0.019
 BMI <2259.6(90/151)50.0(40/80)70.4(50/71)0.011
Cancer, % (n/N)32.9(50/155)34.1(28/82)31.4(22/70)0.722
History of pancreatitis, % (n/N)16.2(25/154)13.3(11/83)19.7(14/71)0.278
First conducted ERCP, % (n/N)34.8(54/155)33.3(28/84)36.6(26/71)0.669
Resident as a main operator, % (n/N)63.9(99/155)71.4(60/84)54.9(39/71)0.033
Serum creatinine before ERCP (mg/dL)0.80 (0.70–0.90)0.80 (0.70–0.90)0.80 (0.70–1.00)0.642
Duration of examination, median (IQR)36.5 (26.0–51.3)37.0 (28.0–50.0)35.0 (23.0–53.0)0.568
 Duration of examination >30 min, % (n/N)63.6(98/154)66.3(55/83)60.6(43/71)0.463
Difficult cannulation, % (n/N)28.4(44/155)27.4(23/84)29.6(21/71)0.763
Procedures for pancreatic duct, % (n/N)68.4(106/155)69.0(58/84)67.6(48/71)0.847
 Pancreatic duct wire, % (n/N)65.2(101/155)65.5(55/84)64.8(46/71)0.929
 Cytology of pancreas duct, % (n/N)19.4(30/155)17.9(15/84)21.1(15/71)0.608
 Pancreatography, % (n/N)31.6(49/155)34.5(29/84)28.2(20/71)0.397
Cytology of bile duct, % (n/N)18.7(29/155)20.2(17/84)16.9(12/71)0.596
EST, % (n/N)26.5(41/155)23.8(20/84)29.6(21/71)0.417
EPBD, % (n/N)5.8(9/155)6.0(5/84)5.6(4/71)0.605
Choledocholithotomy, % (n/N)38.1(59/155)41.7(35/84)33.8(24/71)0.315
Stenting to pancreatic duct, % (n/N)2.6(4/155)2.4(2/84)2.8(2/71)0.624
  • BMI, body mass index; EPBD, endoscopic papillary balloon dilation; ERCP, endoscopic retrograde cholangiopancreatography; EST, endoscopic sphincterotomy.