Accuracy of the algorithm in the validation samples
| Training set— Rheumatological sample* | Validating set— Rheumatological sample | Validating set— General population | |
|---|---|---|---|
| Sensitivity (95% CI) | 96.32 (96.25 to 96.38) | 93.75 (79.19 to 99.23) | 92.50 (79.61 to 98.43) |
| Specificity (95% CI) | 90.33 (90.24 to 90.41) | 90.54 (81.48 to 96.11) | 99.77 (99.61 to 99.87) |
| PPV (95% CI) | 85.04 (80.81 to 88.66) | 81.08 (64.84 to 92.04) | 72.55 (58.26 to 84.11) |
| NPV (95% CI) | 97.74 (95.99 to 98.86) | 97.10 (89.92 to 99.65) | 99.95 (99.85 to 99.99) |
*Bootstrap estimates.
NPV, negative predictive value; PPV, positive predictive value.