Cox proportional HR of pneumonia between patients with non-traumatic intracranial haemorrhage who used proton pump inhibitors (PPIs) (N=434) and those who did not use PPIs (N=1736)
| 95% CI | 95% CI | |||||||
|---|---|---|---|---|---|---|---|---|
| Patients (N) | Pneumonia events (N) | Crude HR | Lower | Upper | Adjusted HR | Lower | Upper | |
| PPI | ||||||||
| No | 1736 | 326 | 1 | 1 | ||||
| Yes | 434 | 142 | 1.70** | 1.40 | 2.08 | 1.61** | 1.32 | 1.97 |
| Gender | ||||||||
| Female | 770 | 151 | 1 | 1 | ||||
| Male | 1400 | 317 | 1.11 | 0.92 | 1.35 | 1.36** | 1.12 | 1.66 |
| Age, years | ||||||||
| 18–39 | 130 | 13 | 1 | 1 | ||||
| 40–64 | 790 | 112 | 1.24 | 0.70 | 2.20 | 1.22 | 0.69 | 2.17 |
| ≥65 | 1250 | 343 | 2.73** | 1.57 | 4.76 | 2.62** | 1.49 | 4.59 |
| Monthly income | ||||||||
| ≤NT$19200 | 1293 | 309 | 1 | 1 | ||||
| >NT$19200 | 877 | 159 | 0.76** | 0.63 | 0.92 | 0.81* | 0.66 | 0.99 |
| Urbanisation | ||||||||
| Urban | 1178 | 250 | 1 | 1 | ||||
| Suburban | 687 | 141 | 0.98 | 0.79 | 1.20 | 1.02 | 0.82 | 1.25 |
| Rural | 305 | 77 | 1.25 | 0.96 | 1.61 | 1.22 | 0.94 | 1.59 |
| CCI | ||||||||
| 0 | 409 | 40 | 1 | 1 | ||||
| 1 | 1128 | 273 | 2.23** | 1.60 | 3.11 | 1.62** | 1.15 | 2.27 |
| ≥2 | 633 | 155 | 2.30** | 1.62 | 3.25 | 1.58* | 1.11 | 2.27 |
*p<0.05, **p<0.01.
CCI,Charlson Comorbidity Index.