Table 3

HR (95% CI) of all-cause and cause-specific mortality associated with sex-specific* quartile of waist circumference

Quartile 1Quartile 2Quartile 3Quartile 4
All-cause mortality
 Number of deaths173185150111
 Mortality rate (SE)†29 (3.5)31 (4.0)28 (3.5)23 (3.0)
 HRs
  Unadjusted1.001.11 (0.86 to 1.43)0.99 (0.71 to 1.39)0.84 (0.61 to 1.17)
  Multivariable adjusted 1‡1.000.92 (0.69 to 1.25)0.87 (0.61 to 1.25)1.04 (0.69 to 1.55)
  Multivariable adjusted 2§1.001.03 (0.77 to 1.37)1.02 (0.73 to 1.42)1.12 (0.77 to 1.61)
Cardiovascular mortality
 Number of deaths75636036
 Mortality rate (SE)†10 (1.7)11 (2.6)9 (1.6)7 (1.6)
 HRs
  Unadjusted1.001.20 (0.70 to 2.07)0.91 (0.57 to 1.45)0.72 (0.40 to 1.31)
  Multivariable adjusted 1‡1.001.00 (0.56 to 1.78)0.80 (0.49 to 1.33)1.09 (0.61 to 1.97)
  Multivariable adjusted 2§1.001.17 (0.66 to 2.10)0.94 (0.59 to 1.50)1.13 (0.64 to 2.00)
Cancer mortality
 Number of deaths31462624
 Mortality rate (SE)†7 (2.2)7 (2.3)8 (2.2)5 (1.4)
 HRs
  Unadjusted1.001.07 (0.46 to 2.47)1.22 (0.58 to 2.55)0.67 (0.27 to 1.65)
  Multivariable adjusted 1‡1.000.89 (0.39 to 2.04)1.04 (0.48 to 2.26)0.78 (0.33 to 1.85)
  Multivariable adjusted 2§1.000.92 (0.44 to 1.90)1.27 (0.57 to 2.82)0.84 (0.34 to 2.08)
Diabetes mortality
 Number of deaths68785434
 Mortality rate (SE)†12 (2.7)13 (2.3)8 (1.4)6 (1.4)
 HRs
  Unadjusted1.001.12 (0.62 to 2.00)0.68 (0.37 to 1.25)0.55 (0.30 to 1.00)
  Multivariable adjusted 1‡1.000.90 (0.49 to 1.66)0.58 (0.31 to 1.08)0.64 (0.34 to 1.18)
  Multivariable adjusted 2§1.001.14 (0.58 to 2.22)0.81 (0.41 to 1.59)0.78 (0.42 to 1.46)
Respiratory mortality
 Number of deaths121399
 Mortality rate (SE)†3 (1.1)3 (1.0)2 (0.8)2 (1.0)
 HRs
  Unadjusted1.001.21 (0.40 to 3.62)0.71 (0.21 to 2.39)0.87 (0.25 to 3.00)
  Multivariable adjusted 1‡1.001.03 (0.35 to 2.98)0.63 (0.18 to 2.24)1.15 (0.35 to 3.76)
  Multivariable adjusted 2§1.000.76 (0.22 to 2.62)0.72 (0.18 to 2.90)0.99 (0.28 to 3.54)
  • *For men: <98.0, 98.0–105.1, 105.2–113.8 and ≥113.9 cm; for women: <90.4, 90.4–100.8, 100.9–111.5 and ≥111.6 cm.

  • †Per 1000 person-years.

  • ‡Adjusted for age, race-ethnicity and sex.

  • §Adjusted for age, race-ethnicity, sex, smoking status, education, income and diabetes duration.