Baseline characteristics of subjects
| Variables | Entire sample | Healthy subjects | External dataset |
|---|---|---|---|
| Demographic information | |||
| N | 2092 | 371 | 88 |
| Age, years | 60.42±8.68 | 56.5±8.75 | 56.61±9.26 |
| Male gender, % | 705 (33.7%) | 78 (21.02%) | 38 (43.18%) |
| BMI, kg/m2 | 24.21±3.36 | 21.57±1.99 | 23.81±2.72 |
| WC, cm | 85.07±9.70 | 77.08±6.83 | 85.09±7.12 |
| SBP, mm Hg | 127.62±18.68 | 114.6±10.93 | 117.85±14.62 |
| DBP, mm Hg | 79.83±9.69 | 73.81±6.92 | 79.23±9.59 |
| Laboratory assays | |||
| FPG, mmol/L | 5.53±1.81 | 4.64±0.59 | 6.84±2.38 |
| PBG, mmol/L | 7.67±3.56 | 5.26±1.11 | 10.29±4.51 |
| FINS, IU/L | 7.19±11.82 | 32.72±13.67 | 8.77±19.31 |
| TC, mmol/L | 5.32±1 | 5.19±0.96 | 5.35±1.05 |
| TG, mmol/L | 1.71±0.98 | 1.1±0.31 | 1.86±1.07 |
| HDL, mmol/L | 1.36±0.32 | 1.55±0.33 | 1.30±0.30 |
| LDL mmol/L | 3.19±0.77 | 3.04±0.77 | 3.14±0.79 |
| UA, μmol/L | 281.21±83.79 | 240.52±68.77 | 292.34±82.65 |
| HRV measurement | |||
| HR, bpm | 72.42±10.13 | 68.39±8.61 | 72.23±9.80 |
| TP, ms2 | 873.95±702.47 | 1127.33±697.28 | 883.69±935.65 |
| LF, ms2 | 190.98±207.88 | 241.35±204.92 | 164.04±220.97 |
| LFn, nu | 21.33±10.66 | 21.44±10.56 | 17.13±8.82 |
| HF, ms2 | 183.05±219.43 | 245.93±230.26 | 208.99±399.68 |
| HFn, nu | 20.67±13.25 | 21.85±12.83 | 20.84±16.23 |
| LF/HF | 1.70±1.98 | 1.53±1.79 | 1.50±1.64 |
| Medical history | |||
| Smoking yes, % | 306 (14.63%) | 35 (9.43%) | 13 (14.77%) |
| HT yes, % | 976 (46.65%) | 0 (0%) | 32 (36.36%) |
| DM yes, % | 446 (21.33%) | 0 (0%) | 53 (60.23%) |
| MS yes, % | 833 (39.82%) | 0 (0%) | 34 (38.64%) |
BMI, body mass index; DBP, diastolic blood pressure; DM, diabetes; FINS, fasting blood insulin; FPG, fasting plasma glucose; HDL, high-density lipoprotein cholesterol; HF, high frequency; HFn, normalised HF; HR, heart rate; HRV, heart rate variability; HT, hypertension; LDL, low density lipoprotein cholesterol; LF, low frequency; LFn, normalised LF; MS, metabolic syndrome; PBG, plasma blood glucose; SBP, systolic blood pressure; TC, serum total cholesterol; TG, triglyceride; TP, total power of variance; UA, uric acid; WC, waist circumference.