Table 3

Subgroup analysis of 5-year disease-free survival according to CXCR expressions for each clinicopathological variable

VariableCXCR3 expressionp ValueCXCR4 expressionp Value
nHigh (%, n=26)Low (%, n=119)High (%, n=56)Low (%, n=89)
Tumour location
 Right side6969.278.60.54574.178.60.673
 Left side7684.685.71.00079.389.40.252
Histological differentiation
 Well2383.382.40.93862.593.30.049
 Moderate9571.481.50.48576.982.10.611
 Poor and Mucinous2783.385.70.90488.983.30.714
TNM stage
 I25100900.47088.993.80.673
 IIA937581.80.59279.481.40.869
 IIB276077.30.57361.585.70.150
Lymphovascular invasion
 Yes1010088.90.70510083.30.439
 No1357681.80.6067584.30.203
Serum CEA (ng/mL)
 <59093.390.70.68785.794.50.149
 ≥55554.568.20.47761.967.60.768
  • CEA, carcinoembryonic antigen; TNM, tumour, node, metastases