Trial participant and design characteristics
| Trial participant and design characteristics (N=90) | n (%) |
|---|---|
| Age group | |
| Adults only | 69 (76.7) |
| Paediatrics only | 15 (16.7) |
| Adults and paediatrics | 5 (5.6) |
| Unclear | 1 (1) |
| Gender | |
| Female | 6 (6.7) |
| Male | 0 (0) |
| Male and female | 84 (93.3) |
| Recruiting newly diagnosed patients | 24 (26.7) |
| Trial recruitment setting* | |
| Secondary | 68 (61) |
| Primary | 53 (58.9) |
| Community | 12(13.3) |
| Emergency | 8 (8.9) |
| Tertiary | 6 (6.7) |
| Social care | 6 (6.7) |
| Blinded trial† | 43 (47.8) |
| Clinician blind | 15/43 (34.9) |
| Participant blind | 19/43 (44.2) |
| Trial involves a placebo | 14 (15.6) |
| If a placebo is involved, do all participants get an active intervention? | 5/14 (35.7) |
*Categories not mutually exclusive.
†Twenty-three trials in which blinding only related to the outcome assessor.