Meta-analysis of withdrawal rate across included studies
| Outcome | Intervention | Comparator | Studies | N | Fixed effects | ||
|---|---|---|---|---|---|---|---|
| RR (95% CI) | p Value | I2 (%) | |||||
| Total withdrawals | Nicergoline | Placebo | 8 | 1234 | 0.92 (0.70 to 1.21) | 0.57 | 0 |
| Nicergoline | Active agents | 3 | 201 | 0.45 (0.10 to 1.95) | 0.28 | 18 | |
| Withdrawals due to AE | Nicergoline | Placebo | 3 | 565 | 1.13 (0.61 to 2.09)* | 0.7 | 0 |
*RR value greater than 1 denotes higher rate of AEs with nicergoline compared with the comparator drug and a value less than 1 denotes vice versa.
AE, adverse event.