Characteristic | HR | 95% CI | p Value |
---|---|---|---|
Grade 3 or 4 MR (significant MR) univariate | 1.47 | 1.13 to 1.92 | 0.005 |
Grade 3 or 4 MR (significant MR) multivariate | 1.83 | 1.28 to 2.62 | <0.001 |
Known lung disease | 2.75 | 1.70 to 4.43 | <0.001 |
MR interaction with known lung disease | 1.98 | 0.44 to 8.82 | 0.005 |
Age group | |||
65–75 years | 3.52 | 1.47 to 8.42 | 0.005 |
75–85 years | 4.73 | 2.17 to 10.3 | <0.001 |
>85 years | 7.01 | 3.24 to 15.2 | <0.001 |
LV dysfunction | |||
Mild | 0.91 | 0.62 to 1.35 | 0.641 |
Moderate | 1.13 | 0.77 to 1.65 | 0.546 |
Severe | 1.75 | 1.19 to 2.58 | 0.004 |
Previous ACS | 1.00 | 0.67 to 1.51 | 0.99 |
GFR <30 mL/min/1.73 m2 | 1.29 | 0.77 to 2.17 | 0.34 |
Previous ACS/CAD interaction with GFR<30 mL/min/1.73 m2 | 2.97 | 1.47 to 5.93 | 0.019 |
Previous ACS/CAD interaction with known lung disease | 1.29 | 0.65 to 2.50 | 0.026 |
Charlson index 1 | 2.05 | 1.26 to 3.32 | 0.004 |
Charlson index 2 | 2.50 | 1.64 to 3.81 | <0.001 |
ACS, acute coronary syndrome; CAD, coronary artery disease; GFR, glomerular filtration rate; LV, left ventricular; MR, mitral regurgitation.