Table 2

Primary publications reporting estimates of the prevalence of possible ghostwriting

PublicationMeasure of possible ghostwriting reported by authorsestimate % (n)
Cross-sectional surveys reporting ghostwriting
Flanagin et al27Unnamed individual who participated in the writing1.4% (11/809) of articles
Wislar et al20Unnamed individual who participated in the writing0.2% (1/622) of articles*
Jacobs and Hamilton, Hamilton and Jacobs 25 33Undisclosed medical writing assistance not qualifying for authorship2005: 61.8% (NR)
2009: 41.7% (NR)
2011: 33.0% (NR) of articles†
Cross-sectional surveys reporting combined ghost authoring and ghostwriting
Flanagin et al27Failure to name, as an author, individuals who made substantial contributions to the research or writing or an unidentified medical writer11.5% (93/809) of articles
Price et al22Failure to name, as an author, individuals who made substantial contributions to the research or writing24.1% (40/166) of authors
Mowatt et al 23Individual merited authorship or had assisted with drafting but not listed as an author or acknowledged8.8% (32/362) of articles
Hao et al32English-language speakers assisted with writing but not identified as authors or acknowledged10.4% (NR) of authors
Dotson and Slaughter28Failure to name, as an author, individuals who made substantial contributions to the research or writing0.9% (1/112) of articles
Wislar et al20Failure to name, as an author, individuals who made substantial contributions to the research or writing of the article or an unnamed individual who participated in the writing7.9% (49/622) of articles
Cross-sectional surveys reporting ghost authoring
Mirzazadeh et al24Failure to name, as an author, individuals who made substantial contributions to the research21.4% (25/NR) of authors
Ghajarzadeh26Failure to name, as an author, students who made substantial contributions to the research‡0.7% (2/296) of articles
Vinther and Rosenberg21Individual merited authorship but not listed as an author2.4% (6/245) of articles
Rees et al31Individual merited authorship but not listed as an author70% (NR/202) of published authors
Publication reviews and descriptive analysis reporting possible ghost authoring or ghostwriting
Healy and Cattell6Published articles coordinated by a medical information company, including acknowledged medical writing support§57.3% (55/96) of articles
Gøtzsche et al30Individuals who wrote the trial protocol, conducted the statistical analyses or wrote the manuscript but were not listed as authors, not members of a study group or steering committee or not disclosed in an acknowledgment75.0% (33/44) of trials
Ross et al8Published reviews associated with Merck support and with a single external author¶69.4% (50/72) of reviews
  • *Available as online supplementary data.

  • †Values represent the mean weighted percentage of publications that were ghostwritten by respondents. Findings were weighted in proportion to the number of manuscripts the respondent wrote per year.

  • ‡Students were classified as ghostwriters if the student was not named as an author and if the results reported in the publications were based on the results of their theses.

  • §Authors conclude data provide quantification of the possible extent of ghostwriting based on a single drug. Of the 55 published articles that were coordinated through a medical information company, 2 included medical writing assistance that was acknowledged in the published article.

  • ¶Published review articles had been identified from correspondence between Merck and a medical publishing company, from Merck publication status reports, or were affiliated with an author named within the correspondence or publication status reports. The authors did not report whether medical writing assistance was acknowledged in the published article.

  • NR, not reported.