Association of signs and symptoms with weight gain
| Present in the episode yes/no Change in weight (g) associated with the symptom presence | Duration Change in weight (g) per day present | |
|---|---|---|
| Anorexia | −46.6 (−87.7, −5.6) | −12.9 (−23.1, −2.7) |
| (p=0.026) | (p=0.013) | |
| Blood in stool (observed by mother) | −2.1 (−61.7, 57.5) | −4.1 (−30.1, 21.9) |
| (p=0.946) | (p=0.757) | |
| Blood in stool (observed by laboratory technician) | 10.3 (−72.8, 93.5) | N/A |
| (p=0.807) | ||
| Fever | −47.9 (−89.1, −6.5) | −19.5 (−36.7, −2.3) |
| (p=0.023) | (p=0.026) | |
| Nausea | −1.5 (−60.8, 57.9) | −2.2 (−29.6, 25.2) |
| (p=0.962) | (p=0.875) | |
| Malaise | −49.5 (−85.0, −14.1) | −9.9 (−18.3, −0.4) |
| (p=0.006) | (p=0.022) | |
| Mucus in stool (observed by mother) | −4.5 (−47.3, 38.3) | −0.1 (−15.0, 15.0) |
| (p=0.837) | (p=0.998) | |
| Mucus in stool (observed by laboratory technician) | 2.9 (−34.8, 40.6) | N/A |
| (p=0.879) | ||
| Stomach pain | −13.9 (−48.9, 21.0) | −5.8 (−13.7, 2.2) |
| (p=0.435) | (p=0.156) | |
| Vomiting | −57.0 (−109.3, −4.7) | −28.0 (−52.9, 30.8) |
| (p=0.033) | (p=0.028) | |
| Four or more liquid stools in a 24 h period | −43.1 (−79.6, −6.6) | −23.5 (−37.5, −9.5) |
| (p=0.021) | (p=0.001) | |
| Maximum number of stools per 24 h period (continuous) | −9.9 (−18.0, −1.8) | N/A |
| (p=0.016) | ||
| Episode duration (per day—continuous) | −5.1 (−12.5, 2.4) | N/A |
| (p=0.181) |
In the below model, age (as fractional polynomials, term 1=age−2−1.16 and term 2=ln(age)×age−2 − 0.08), season (with sine/cosine terms), and an first order autoregressive1 covariance structure.