Table 5

Adverse genitourinary events: ORs (posterior mean with 95% intervals) for each pair-wise comparison of interventions, based on direct evidence alone (lower-left triangle) or direct and indirect evidence (upper-right triangle)

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  • Lower-left results compare row-defining interventions against column-defining interventions. Upper-right results compare column-defining interventions against row-defining interventions.

  • The comparison of prostatectomy with observational management was not linked to the rest of the network, so this evidence was included in the meta-analysis of direct comparisons only.

  • In the meta-analysis of direct comparisons (reported in lower-left triangle), between-trial heterogeneity τ² was estimated as 0.04 (95% interval 0.003 to 0.29).

    In the network meta-analysis (reported in upper-right triangle), between-trial heterogeneity τ² was estimated as 0.04 (95% interval 0.002 to 0.26).

  • The small superscript numbers in the cells of lower-left triangle indicate the numbers of randomised trials which compared the two interventions directly.

  • HD, high dose; LD, low dose.