Observed versus expected mortality ratio, estimated over 4 years, standardised mortality ratio, AR, absolute excess risk and HR for mortality by age group and period among 37276 men and women aged <55 years with first AMI
| Age, period | Observed* | Expected† | SMR (95% CI) | AR‡ | AER§ | HR (95% CI)¶ | HR (95% CI)** |
|---|---|---|---|---|---|---|---|
| Men 25–44 | |||||||
| 1987–1991 | 113 | 16 | 6.88 (5.67 to 8.20) | 1.61 | 1.38 | 1 (ref) | 1 (ref) |
| 1992–1996 | 81 | 13 | 6.16 (4.89 to 7.57) | 1.25 | 1.05 | 0.76 (0.57 to 1.01) | 0.73 (0.55 to 0.98) |
| 1997–2001 | 58 | 10 | 5.70 (4.33 to 7.27) | 1.00 | 0.83 | 0.60 (0.43 to 0.82) | 0.53 (0.38 to 0.73) |
| 2002–2006 | 36 | 8 | 4.34 (3.04 to 5.87) | 0.65 | 0.50 | 0.41 (0.28 to 0.60) | 0.30 (0.20 to 0.44) |
| Men 45–54 | |||||||
| 1987–1991 | 465 | 125 | 3.72 (3.39 to 4.07) | 2.10 | 1.53 | 1 (ref) | 1 (ref)†† |
| 1992–1996 | 379 | 119 | 3.20 (2.88 to 3.53) | 1.56 | 1.07 | 0.74 (0.65 to 0.85) | 0.70 (0.61 to 0.81) |
| 1997–2001 | 289 | 108 | 2.69 (2.39 to 3.00) | 1.22 | 0.77 | 0.57 (0.49 to 0.66) | 0.50 (0.43 to 0.58) |
| 2002–2006 | 215 | 89 | 2.43 (2.12 to 2.76) | 0.99 | 0.59 | 0.47 (0.40 to 0.56) | 0.32 (0.27 to 0.39) |
| Women 25–44 | |||||||
| 1987–1991 | 34 | 2 | 17.55 (12.15 to 23.94) | 2.39 | 2.26 | 1 (ref) | 1 (ref) |
| 1992–1996 | 28 | 2 | 17.99 (11.95 to 25.27) | 2.17 | 2.05 | 0.93 (0.56 to 1.55) | 0.85 (0.51 to 1.42) |
| 1997–2001 | 10 | 2 | 6.07 (2.89 to 10.42) | 0.63 | 0.52 | 0.27 (0.13 to 0.55) | 0.28 (0.14 to 0.56) |
| 2002–2006 | 21 | 2 | 13.53 (8.36 to 19.93) | 1.26 | 1.17 | 0.55 (0.32 to 0.94) | 0.47 (0.27 to 0.83) |
| Women 45–54 | |||||||
| 1987–1991 | 101 | 15 | 6.90 (5.62 to 8.31) | 2.25 | 1.93 | 1 (ref) | 1 (ref)‡‡ |
| 1992–1996 | 76 | 16 | 4.63 (3.65 to 5.73) | 1.45 | 1.14 | 0.64 (0.48 to 0.87) | 0.56 (0.42 to 0.76) |
| 1997–2001 | 68 | 19 | 3.58 (2.78 to 4.48) | 1.08 | 0.78 | 0.49 (0.36 to 0.66) | 0.44 (0.32 to 0.60) |
| 2002–2006 | 102 | 16 | 6.42 (5.24 to 7.73) | 1.72 | 1.45 | 0.77 (0.59 to 1.02) | 0.53 (0.39 to 0.71) |
*Observed number of deaths in the study population.
†Expected number of deaths in the general population.
‡AR per 100 person-years.
§Absolute excess risk per 100 person-years.
¶Age adjusted.
**Multiadjusted for age, diabetes, hypertension, valvular, congenital heart disease, stroke, chronical respiratory disease, malignancy and renal failure.
†Adjusted for changes and interaction over time, malignancy.
‡‡Chronic respiratory disease.
AER, absolute excess risk; AMI, acute myocardial infarction; AR, absolute risk; SMR, standardised mortality ratio.